Literature DB >> 14688147

Antibody-mediated neutralization of pertussis toxin-induced mitogenicity of human peripheral blood mononuclear cells.

Scott H Millen1, David I Bernstein, Beverly Connelly, Joel I Ward, Swei-Ju Chang, Alison A Weiss.   

Abstract

Antibody-mediated neutralization of pertussis toxin-induced proliferation of human peripheral blood mononuclear cells (PBMC) was assessed using alamarBlue and compared with results from the Chinese hamster ovary (CHO) cell assay using sera from vaccinated adults and convalescent children. Neutralization values for the CHO assay were similar for vaccinated and convalescent subjects; however. the convalescent group had higher titers in the PBMC assay. Results for pertussis toxin neutralization with the CHO assay appear to be distinct from those with the PBMC assay.

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Year:  2004        PMID： 14688147      PMCID： PMC343983          DOI： 10.1128/IAI.72.1.615-620.2004

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  38 in total

1.  Reversal of the CD4(+)/CD8(+) T-cell ratio in lymph node cells upon in vitro mitogenic stimulation by highly purified, water-soluble S3-S4 dimer of pertussis toxin.

Authors:  R Latif; N Kerlero de Rosbo; T Amarant; R Rappuoli; G Sappler; A Ben-Nun
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

2.  Phagocytosis of Bordetella pertussis incubated with convalescent serum.

Authors:  Paula S Mobberley-Schuman; Beverly Connelly; Alison A Weiss
Journal:  J Infect Dis       Date:  2003-04-30       Impact factor: 5.226

Review 3.  Pertussis toxin: the cause of the harmful effects and prolonged immunity of whooping cough. A hypothesis.

Authors:  M Pittman
Journal:  Rev Infect Dis       Date:  1979 May-Jun

4.  Levels of anti-pertussis antibodies related to protection after household exposure to Bordetella pertussis.

Authors:  J Storsaeter; H O Hallander; L Gustafsson; P Olin
Journal:  Vaccine       Date:  1998-12       Impact factor: 3.641

5.  Pertussis toxin and extracytoplasmic adenylate cyclase as virulence factors of Bordetella pertussis.

Authors:  A A Weiss; E L Hewlett; G A Myers; S Falkow
Journal:  J Infect Dis       Date:  1984-08       Impact factor: 5.226

6.  Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin.

Authors:  G M Bokoch; A G Gilman
Journal:  Cell       Date:  1984-12       Impact factor: 41.582

7.  Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein.

Authors:  T Katada; M Ui
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

8.  Induction of a novel morphological response in Chinese hamster ovary cells by pertussis toxin.

Authors:  E L Hewlett; K T Sauer; G A Myers; J L Cowell; R L Guerrant
Journal:  Infect Immun       Date:  1983-06       Impact factor: 3.441

9.  A role of the B-oligomer moiety of islet-activating protein, pertussis toxin, in development of the biological effects on intact cells.

Authors:  M Tamura; K Nogimori; M Yajima; K Ase; M Ui
Journal:  J Biol Chem       Date:  1983-06-10       Impact factor: 5.157

10.  ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing biosignaling.

Authors:  F Okajima; M Ui
Journal:  J Biol Chem       Date:  1984-11-25       Impact factor: 5.157
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  7 in total

1.  Acellular pertussis vaccines and complement killing of Bordetella pertussis.

Authors:  Alison A Weiss; Angela K Patton; Scott H Millen; Swei-Ju Chang; Joel I Ward; David I Bernstein
Journal:  Infect Immun       Date:  2004-12       Impact factor: 3.441

2.  Toxicity of anthrax toxin is influenced by receptor expression.

Authors:  Sarah C Taft; Alison A Weiss
Journal:  Clin Vaccine Immunol       Date:  2008-07-02

3.  Neutralizing antibodies and persistence of immunity following anthrax vaccination.

Authors:  James F Hanson; Sarah C Taft; Alison A Weiss
Journal:  Clin Vaccine Immunol       Date:  2006-02

4.  Single Amino Acid Polymorphisms of Pertussis Toxin Subunit S2 (PtxB) Affect Protein Function.

Authors:  Scott H Millen; Mineo Watanabe; Eiji Komatsu; Fuminori Yamaguchi; Yuki Nagasawa; Eri Suzuki; Haleigh Monaco; Alison A Weiss
Journal:  PLoS One       Date:  2015-09-16       Impact factor: 3.240

5.  Pertussis toxin B-pentamer mediates intercellular transfer of membrane proteins and lipids.

Authors:  Scott H Millen; Olivia D Schneider; William E Miller; John J Monaco; Alison A Weiss
Journal:  PLoS One       Date:  2013-09-03       Impact factor: 3.240

Review 6.  Evaluation of Anti-PT Antibody Response after Pertussis Vaccination and Infection: The Importance of Both Quantity and Quality.

Authors:  Alex-Mikael Barkoff; Aapo Knuutila; Jussi Mertsola; Qiushui He
Journal:  Toxins (Basel)       Date:  2021-07-21       Impact factor: 4.546

Review 7.  Bacterial Vaccine Antigen Discovery in the Reverse Vaccinology 2.0 Era: Progress and Challenges.

Authors:  Fadil A Bidmos; Sara Siris; Camilla A Gladstone; Paul R Langford
Journal:  Front Immunol       Date:  2018-10-08       Impact factor: 7.561
  7 in total

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