Literature DB >> 6445767

Impromidine (SK & F 92676) acts as a partial agonist on the isolated whole stomach of the rat.

M Parsons, C Sykes.   

Abstract

The present secretory studies on the isolated stomach of the rat provide evidence that impromidine acts as a partial agonist at the histamine H2-receptors. It was found to be 100 times more potent than histamine but with a maximal response only 50% that obtained with histamine.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6445767      PMCID： PMC2044178          DOI： 10.1111/j.1476-5381.1980.tb10874.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  2 in total

1.  A quantitative study of metiamide, a histamine H2-antagonist, on the isolated whole rat stomach.

Authors:  K T Bunce; M E Parsons
Journal:  J Physiol       Date:  1976-06       Impact factor: 5.182

2.  Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors.

Authors:  G J Durant; W A Duncan; C R Ganellin; M E Parsons; R C Blakemore; A C Rasmussen
Journal:  Nature       Date:  1978-11-23       Impact factor: 49.962
  2 in total
  13 in total

Review 1.  An update on histamine receptors and the gastrointestinal tract.

Authors:  B I Hirschowitz
Journal:  Dig Dis Sci       Date:  1985-10       Impact factor: 3.199

2.  The determination of receptor constants for histamine H2-agonists in the guinea-pig isolated right atrium using an irreversible H2-antagonist.

Authors:  T J Rising; A Steward
Journal:  Br J Pharmacol       Date:  1986-01       Impact factor: 8.739

3.  Characterization of histamine H2-receptors in human neutrophils with a series of guanidine analogues of impromidine. Are cell type-specific H2-receptors involved in the regulation of NADPH oxidase?

Authors:  R Burde; A Buschauer; R Seifert
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-05       Impact factor: 3.000

4.  Presynaptic histamine H2 receptors modulate the sympathetic nerve transmission in the isolated rat vas deferens; no role for H3-receptors.

Authors:  E Poli; S Todorov; C Pozzoli; G Bertaccini
Journal:  Agents Actions       Date:  1994-10

5.  The relative contribution of affinity and efficacy to agonist activity: organ selectivity of noradrenaline and oxymetazoline with reference to the classification of drug receptors.

Authors:  T P Kenakin
Journal:  Br J Pharmacol       Date:  1984-01       Impact factor: 8.739

6.  Effect of intracerebroventricular impromidine on pituitary-adrenocortical response to stress in rats.

Authors:  J Bugajski; A Gadek
Journal:  Agents Actions       Date:  1984-06

7.  In vitro cardiac pharmacology of the new histamine H2-receptor agonist amthamine: comparisons with histamine and dimaprit.

Authors:  E Poli; C Pozzoli; G Coruzzi; G Bertaccini; H Timmerman
Journal:  Agents Actions       Date:  1993-09

8.  The new potent and selective histamine H2 receptor agonist amthamine as a tool to study gastric secretion.

Authors:  G Coruzzi; H Timmerman; M Adami; G Bertaccini
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-07       Impact factor: 3.000

9.  Effects of impromidine, a specific H2-receptor agonist and 2(2-pyridyl)-ethylamine, an H1-receptor agonist, on stimulation-induced release of [3H]-noradrenaline in guinea-pig isolated atria.

Authors:  M J Rand; D F Story; H Wong-Dusting
Journal:  Br J Pharmacol       Date:  1982-06       Impact factor: 8.739

10.  Effect of impromidine (SK&F 92676) on the isolated papillary muscle of the guinea-pig.

Authors:  G Bertaccini; G Coruzzi
Journal:  Br J Pharmacol       Date:  1981-02       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.