| Literature DB >> 6435517 |
Abstract
The MICs of imipenem and piperacillin, alone and in combination, against Pseudomonas aeruginosa were determined in a checkerboard titration microdilution assay. A dramatic, one-way antagonism of imipenem for piperacillin was demonstrated in 28 of the 35 strains examined; antagonism was associated with the induction of a beta-lactamase.Entities:
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Year: 1984 PMID: 6435517 PMCID: PMC284137 DOI: 10.1128/AAC.26.2.272
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191