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Literature DB >> 3111357

Synergism of the combinations of imipenem plus ciprofloxacin and imipenem plus amikacin against Pseudomonas aeruginosa and other bacterial pathogens.

C I Bustamante, G L Drusano, R C Wharton, J C Wade.

Abstract

The combinations of imipenem plus ciprofloxacin and imipenem plus amikacin were investigated for their activity against Pseudomonas aeruginosa and other bacterial pathogens. For imipenem-susceptible P. aeruginosa, synergy of imipenem plus ciprofloxacin and imipenem plus amikacin was observed against 36 and 45% of the strains, respectively. The incidence of synergy against imipenem-resistant isolates of P. aeruginosa was 10% for both combinations. Antagonism was not observed with either combination.

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Year: 1987 PMID： 3111357 PMCID： PMC174794 DOI： 10.1128/AAC.31.4.632

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

18 in total

1. Serum bactericidal activity and killing rate for volunteers receiving imipenem, imipenem plus amikacin, and ceftazidime plus amikacin against Pseudomonas aeruginosa.

Authors: P Van der Auwera; J Klastersky; H Lagast; M Husson
Journal: Antimicrob Agents Chemother Date: 1986-07 Impact factor: 5.191

2. Imipenem antagonism of the in vitro activity of piperacillin against Pseudomonas aeruginosa.

Authors: M A Bertram; L S Young
Journal: Antimicrob Agents Chemother Date: 1984-08 Impact factor: 5.191

3. Ciprofloxacin, a quinolone carboxylic acid compound active against aerobic and anaerobic bacteria.

Authors: N X Chin; H C Neu
Journal: Antimicrob Agents Chemother Date: 1984-03 Impact factor: 5.191

4. In vitro activity of ciprofloxacin, a new carboxyquinoline antimicrobial agent.

Authors: G M Eliopoulos; A Gardella; R C Moellering
Journal: Antimicrob Agents Chemother Date: 1984-03 Impact factor: 5.191

Review 5. Synergistic combinations of antibiotics in gram-negative bacillary infections.

Authors: J Klastersky; S H Zinner
Journal: Rev Infect Dis Date: 1982 Mar-Apr

6. Potential of imipenem as single-agent empiric antibiotic therapy of febrile neutropenic patients with cancer.

Authors: J C Wade; H C Standiford; G L Drusano; D E Johnson; M R Moody; C I Bustamante; J H Joshi; C deJongh; S C Schimpff
Journal: Am J Med Date: 1985-06-07 Impact factor: 4.965

7. In vitro evaluation of N-formimidoyl thienamycin (MK0787) combined with amikacin against gram-negative bacilli and Staphylococcus aureus.

Authors: M Díez Enciso; M Mateos Lindemann; A Gutiérrez Altés
Journal: Antimicrob Agents Chemother Date: 1982-12 Impact factor: 5.191

8. Imipenem-induced resistance to antipseudomonal beta-lactams in Pseudomonas aeruginosa.

Authors: F Tausk; M E Evans; L S Patterson; C F Federspiel; C W Stratton
Journal: Antimicrob Agents Chemother Date: 1985-07 Impact factor: 5.191

9. Synergism at clinically attainable concentrations of aminoglycoside and beta-lactam antibiotics.

Authors: T M Hooton; A D Blair; M Turck; G W Counts
Journal: Antimicrob Agents Chemother Date: 1984-10 Impact factor: 5.191

10. Moxalactam plus piperacillin versus moxalactam plus amikacin in febrile granulocytopenic patients.

Authors: D J Winston; R C Barnes; W G Ho; L S Young; R E Champlin; R P Gale
Journal: Am J Med Date: 1984-09 Impact factor: 4.965

13 in total

1. In vitro activity of ciprofloxacin in combination with ceftazidime, aztreonam, and azlocillin against multiresistant isolates of Pseudomonas aeruginosa.

Authors: C I Bustamante; R C Wharton; J C Wade
Journal: Antimicrob Agents Chemother Date: 1990-09 Impact factor: 5.191

Review 2. Synergy and antagonism of combinations with quinolones.

Authors: H C Neu
Journal: Eur J Clin Microbiol Infect Dis Date: 1991-04 Impact factor: 3.267

3. In vitro activity of aztreonam, cefotaxime, ceftazidime and imipenem combined with ciprofloxacin against gram-negative bacilli and compared with amikacin combinations against Pseudomonas aeruginosa.

Authors: M Díez Enciso
Journal: Eur J Clin Microbiol Infect Dis Date: 1991-02 Impact factor: 3.267

Review 4. Antibiotic combinations: should they be tested?

Authors: G M Eliopoulos; C T Eliopoulos
Journal: Clin Microbiol Rev Date: 1988-04 Impact factor: 26.132

5. Synergistic activity of aminoglycoside-beta-lactam combinations against Pseudomonas aeruginosa with an unusual aminoglycoside antibiogram.

Authors: R B Clark; C B Pakiz; M K Hostetter
Journal: Med Microbiol Immunol Date: 1990 Impact factor: 3.402

6. In vitro activity of trovafloxacin in combination with ceftazidime, meropenem, and amikacin.

Authors: D Milatovic; C Wallrauch
Journal: Eur J Clin Microbiol Infect Dis Date: 1996-08 Impact factor: 3.267

7. Cross-resistance of Pseudomonas aeruginosa to ciprofloxacin, extended-spectrum beta-lactams, and aminoglycosides and susceptibility to antibiotic combinations.

Authors: A W Chow; J Wong; K H Bartlett; S D Shafran; H G Stiver
Journal: Antimicrob Agents Chemother Date: 1989-08 Impact factor: 5.191