Literature DB >> 6433912

The human apolipoprotein A-II gene is located on chromosome 1.

K J Lackner, S W Law, H B Brewer, A Y Sakaguchi, S L Naylor.   

Abstract

Apolipoprotein (apo) A-II is a major constituent of high density lipoproteins (HDL). The gene for apoA-II has been localized to the p21----qter region of chromosome 1 in man by Southern blot hybridization analysis of DNA from human-mouse cell hybrids using a cloned human apoA-II cDNA probe. The regional assignment was established using two hybrids carrying a reciprocal translocation involving chromosomes 1 and 2. Comparison with previously established gene loci on chromosomes 1 suggests that apoA-II may reside in a conserved linkage group with renin and peptidase C. On the other hand, apoA-II is not linked to the apoA-I gene, which has been localized previously to chromosome 11.

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Year:  1984        PMID: 6433912     DOI: 10.1016/0006-291x(84)91172-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  12 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

3.  The human apolipoprotein A-II gene: complete nucleic acid sequence and genomic organization.

Authors:  K J Lackner; S W Law; H B Brewer
Journal:  Nucleic Acids Res       Date:  1985-06-25       Impact factor: 16.971

4.  Confirmation of the close linkage between the loci for human apolipoproteins AI and AIV by the use of a cloned cDNA probe and two restriction site polymorphisms.

Authors:  S Rogne; O Myklebost; B Olaisen; T Gedde-Dahl; H Prydz
Journal:  Hum Genet       Date:  1986-01       Impact factor: 4.132

5.  The gene for human apolipoprotein CI is located 4.3 kilobases away from the apolipoprotein E gene on chromosome 19.

Authors:  O Myklebost; S Rogne
Journal:  Hum Genet       Date:  1986-08       Impact factor: 4.132

6.  Retinoids increase human apolipoprotein A-11 expression through activation of the retinoid X receptor but not the retinoic acid receptor.

Authors:  N Vu-Dac; K Schoonjans; V Kosykh; J Dallongeville; R A Heyman; B Staels; J Auwerx
Journal:  Mol Cell Biol       Date:  1996-07       Impact factor: 4.272

7.  High density lipoprotein deficiency with xanthomas. A defect in reverse cholesterol transport caused by a point mutation in the apolipoprotein A-I gene.

Authors:  K J Lackner; H Dieplinger; G Nowicka; G Schmitz
Journal:  J Clin Invest       Date:  1993-11       Impact factor: 14.808

8.  DNA polymorphisms of the apolipoprotein AII and AI-CIII-AIV genes: a study in men selected for differences in high-density-lipoprotein cholesterol concentration.

Authors:  A M Kessling; J Rajput-Wiliams; D Bainton; J Scott; N E Miller; I Baker; S E Humphries
Journal:  Am J Hum Genet       Date:  1988-03       Impact factor: 11.025

9.  Regional mapping of human chromosome 19: organization of genes for plasma lipid transport (APOC1, -C2, and -E and LDLR) and the genes C3, PEPD, and GPI.

Authors:  A J Lusis; C Heinzmann; R S Sparkes; J Scott; T J Knott; R Geller; M C Sparkes; T Mohandas
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

10.  A DNA polymorphism of the apoprotein AII gene in hypertriglyceridaemia.

Authors:  G A Ferns; C S Shelley; J Stocks; A Rees; H Paul; F Baralle; D J Galton
Journal:  Hum Genet       Date:  1986-11       Impact factor: 4.132

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