Literature DB >> 2989800

The human apolipoprotein A-II gene: complete nucleic acid sequence and genomic organization.

K J Lackner, S W Law, H B Brewer.   

Abstract

The gene for human apolipoprotein (apo) A-II has been isolated from a human genomic DNA library. The cloned fragment was approximately 14 kilobase-pair (kb) long, and extended about 9.0 kb upstream as well as 3.5 kb downstream from the apoA-II gene, which was contained within a 3.1 kb HindIII fragment of human DNA. The complete nucleic acid sequence of the apoA-II gene has been determined, establishing that the apoA-II gene is interrupted by three intervening sequences of 182, 293, and 395 bp. The second intron is of particular interest, because it contains a 33 bp sequence of alternating G and T residues very close to the 3' splice site which has the potential to form a left handed Z-helix structure in vivo. A restriction fragment length polymorphism 3' from the apoA-II gene has been detected which may serve as a marker for the long arm of chromosome 1 in linkage analyses.

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Year:  1985        PMID： 2989800      PMCID： PMC321808          DOI： 10.1093/nar/13.12.4597

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  34 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

Authors:  L M Kunkel; K D Smith; S H Boyer; D S Borgaonkar; S S Wachtel; O J Miller; W R Breg; H W Jones; J M Rary
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

3.  Polypeptide distribution of the main lipoprotein density classes separated from human plasma by rate zonal ultracentrifugation.

Authors:  G M Kostner; J R Patsch; S Sailer; H Braunsteiner; A Holasek
Journal:  Eur J Biochem       Date:  1974-06-15

4.  Amino acid sequence of human apoLp-Gln-II (apoA-II), an apolipoprotein isolated from the high-density lipoprotein complex.

Authors:  H B Brewer; S E Lux; R Ronan; K M John
Journal:  Proc Natl Acad Sci U S A       Date:  1972-05       Impact factor: 11.205

Review 5.  Organization and expression of eucaryotic split genes coding for proteins.

Authors:  R Breathnach; P Chambon
Journal:  Annu Rev Biochem       Date:  1981       Impact factor: 23.643

6.  Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

Authors:  Y Nishioka; P Leder
Journal:  J Biol Chem       Date:  1980-04-25       Impact factor: 5.157

7.  The ovalbumin gene-sequence of putative control regions.

Authors:  C Benoist; K O'Hare; R Breathnach; P Chambon
Journal:  Nucleic Acids Res       Date:  1980-01-11       Impact factor: 16.971

8.  Sequencing end-labeled DNA with base-specific chemical cleavages.

Authors:  A M Maxam; W Gilbert
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

9.  HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study.

Authors:  W P Castelli; J T Doyle; T Gordon; C G Hames; M C Hjortland; S B Hulley; A Kagan; W J Zukel
Journal:  Circulation       Date:  1977-05       Impact factor: 29.690

10.  Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes.

Authors:  J L Slightom; A E Blechl; O Smithies
Journal:  Cell       Date:  1980-10       Impact factor: 41.582
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  8 in total

1.  Homozygous hypobetalipoproteinemia: a disease distinct from abetalipoproproteinemia at the molecular level.

Authors:  R S Ross; R E Gregg; S W Law; J C Monge; S M Grant; K Higuchi; T J Triche; J Jefferson; H B Brewer
Journal:  J Clin Invest       Date:  1988-02       Impact factor: 14.808

2.  Setting the course for apoAII: a port in sight?

Authors:  Henry J Pownall; Baiba K Gillard; Antonio M Gotto
Journal:  Clin Lipidol       Date:  2013-10

3.  Use of variable simple sequence motifs as genetic markers: application to study of myotonic dystrophy.

Authors:  H J Smeets; H G Brunner; H H Ropers; B Wieringa
Journal:  Hum Genet       Date:  1989-10       Impact factor: 4.132

4.  Retinoids increase human apolipoprotein A-11 expression through activation of the retinoid X receptor but not the retinoic acid receptor.

Authors:  N Vu-Dac; K Schoonjans; V Kosykh; J Dallongeville; R A Heyman; B Staels; J Auwerx
Journal:  Mol Cell Biol       Date:  1996-07       Impact factor: 4.272

5.  Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia.

Authors:  K J Lackner; J C Monge; R E Gregg; J M Hoeg; T J Triche; S W Law; H B Brewer
Journal:  J Clin Invest       Date:  1986-12       Impact factor: 14.808

6.  High density lipoprotein deficiency with xanthomas. A defect in reverse cholesterol transport caused by a point mutation in the apolipoprotein A-I gene.

Authors:  K J Lackner; H Dieplinger; G Nowicka; G Schmitz
Journal:  J Clin Invest       Date:  1993-11       Impact factor: 14.808

7.  Human apolipoprotein B (apoB) mRNA: identification of two distinct apoB mRNAs, an mRNA with the apoB-100 sequence and an apoB mRNA containing a premature in-frame translational stop codon, in both liver and intestine.

Authors:  K Higuchi; A V Hospattankar; S W Law; N Meglin; J Cortright; H B Brewer
Journal:  Proc Natl Acad Sci U S A       Date:  1988-03       Impact factor: 11.205

8.  Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor.

Authors:  N Vu-Dac; K Schoonjans; V Kosykh; J Dallongeville; J C Fruchart; B Staels; J Auwerx
Journal:  J Clin Invest       Date:  1995-08       Impact factor: 14.808
  8 in total

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