Literature DB >> 6430233

Mutagenicity of tetramic mycotoxin cyclopiazonic acid.

W G Sorenson, J D Tucker, J P Simpson.   

Abstract

Cyclopiazonic acid was shown to be mutagenic to Salmonella typhimurium TA98 and TA100 in the presence of metabolic activation. The activity of cyclopiazonic acid in the presence of aflatoxin B1 was studied in complete factorial experiments with strain TA98. Both mycotoxins produced significant mutagenic activity and in combination. The activity in combination appeared to be additive rather than synergistic. The specific activity of cyclopiazonic acid was estimated to be approximately 140 revertants per mu mol in strain TA98.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6430233      PMCID： PMC240247          DOI： 10.1128/aem.47.6.1355-1357.1984

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  11 in total

1.  Structure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogs.

Authors:  G N Wogan; G S Edwards; P M Newberne
Journal:  Cancer Res       Date:  1971-12       Impact factor: 12.701

2.  The isolation and structure of cyclopiazonic acid, a toxic metabolite of Penicillium cyclopium Westling.

Authors:  C W Holzapfel
Journal:  Tetrahedron       Date:  1968-03       Impact factor: 2.457

3.  The acute toxicity of the mycotoxin cyclopiazonic acid to rats.

Authors:  I F Purchase
Journal:  Toxicol Appl Pharmacol       Date:  1971-01       Impact factor: 4.219

4.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

Authors:  B N Ames; J Mccann; E Yamasaki
Journal:  Mutat Res       Date:  1975-12       Impact factor: 2.433

Review 5.  Aflatoxin mutagenesis.

Authors:  T M Ong
Journal:  Mutat Res       Date:  1975       Impact factor: 2.433

6.  Production of cyclopiazonic acid by Aspergillus flavus Link.

Authors:  K C Luk; B Kobbe; J M Townsend
Journal:  Appl Environ Microbiol       Date:  1977-01       Impact factor: 4.792

7.  Mycotoxins of Aspergillus oryzae strains for use in the food industry as starters and enzyme producing molds.

Authors:  R Orth
Journal:  Ann Nutr Aliment       Date:  1977

8.  Cyclopiazonic acid production by aflatoxigenic and non-aflatoxigenic strains of Aspergillus flavus.

Authors:  R T Gallagher; J L Richard; H M Stahr; R J Cole
Journal:  Mycopathologia       Date:  1978-12-29       Impact factor: 2.574

9.  Mutagenicity to Salmonella typhimurium of some Aspergillus and Penicillium mycotoxins.

Authors:  F C Wehner; P G Thiel; S J van Rensburg; I P Demasius
Journal:  Mutat Res       Date:  1978-11       Impact factor: 2.433

10.  Cyclopiazonic acid production by Penicillium camemberti Thom and natural occurrence of this mycotoxin in cheese.

Authors:  J Le Bars
Journal:  Appl Environ Microbiol       Date:  1979-12       Impact factor: 4.792
View more
  3 in total

1.  Heterokaryosis between Aspergillus oryzae cyclopiazonic acid-defective strains: method for estimating the risk of inducing toxin production among cyclopiazonic acid-defective industrial strains.

Authors:  O Benkhemmar; F Gaudemer; I Bouvier-Fourcade
Journal:  Appl Environ Microbiol       Date:  1985-10       Impact factor: 4.792

2.  Evaluation of toxicity of Cercospora piaropi in a mycoherbicide formulation by using bacterial bioluminescence and the Ames mutagenicity tests.

Authors:  Maricela Martínez Jiménez; Ana María Sandoval Villasana
Journal:  Mycopathologia       Date:  2008-10-19       Impact factor: 2.574

3.  Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli.

Authors:  Sebastian Theobald; Tammi C Vesth; Mikael R Andersen
Journal:  BMC Genomics       Date:  2019-11-13       Impact factor: 3.969
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.