Literature DB >> 6429128

Maprotiline poisoning: a case of cardiotoxicity and myoclonic seizures.

J Parker, H Lahmeyer.   

Abstract

A 64-year-old man ingested 4500 mg of maprotiline hydrochloride. He developed major motor myoclonic seizures, first-degree AV block, intraventricular conduction delay, hypotension, and urinary retention. Myoclonic seizures have not been previously reported with maprotiline toxicity.

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Year:  1984        PMID： 6429128

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN： 0160-6689            Impact factor:   4.384


  3 in total

Review 1.  Drug-induced urinary retention: incidence, management and prevention.

Authors:  Katia M C Verhamme; Miriam C J M Sturkenboom; Bruno H Ch Stricker; Ruud Bosch
Journal:  Drug Saf       Date:  2008       Impact factor: 5.606

2.  Cardiotoxicity associated with an intentional overdose of maprotiline and perphenazine: a case report.

Authors:  D T Jolly; I G Stiell
Journal:  Can Fam Physician       Date:  1987-11       Impact factor: 3.275

3.  Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels.

Authors:  Claudia Kiesecker; Markus Alter; Sven Kathöfer; Edgar Zitron; Eberhard P Scholz; Dierk Thomas; Jörg Kreuzer; Hugo A Katus; Alexander Bauer; Christoph A Karle
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2006-05-12       Impact factor: 3.000
  3 in total

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