Literature DB >> 21264008

Cardiotoxicity associated with an intentional overdose of maprotiline and perphenazine: a case report.

D T Jolly, I G Stiell.   

Abstract

Cardiotoxicity is a life-threatening complication of an intentional overdose of cyclic antidepressant and phenothiazine drugs. This case report illustrates the severe conduction abnormalities that can accompany a massive ingestion of maprotiline and perphenazine. The patient's condition was further complicated by the unexpected finding of hypothermia.

Entities:  

Year:  1987        PMID： 21264008      PMCID： PMC2218673     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  19 in total

1.  Tricyclic antidepressant overdosage: experimental studies on the management of circulatory complications.

Authors:  T C Brown
Journal:  Clin Toxicol       Date:  1976       Impact factor: 4.467

2.  Maprotiline poisoning: a case of cardiotoxicity and myoclonic seizures.

Authors:  J Parker; H Lahmeyer
Journal:  J Clin Psychiatry       Date:  1984-07       Impact factor: 4.384

3.  Effects of self poisoning with maprotiline.

Authors:  K Knudsen; A Heath
Journal:  Br Med J (Clin Res Ed)       Date:  1984-02-25

4.  Use of sodium bicarbonate to treat tricyclic antidepressant-induced arrhythmias in a patient with alkalosis.

Authors:  D W Molloy; S B Penner; J Rabson; K W Hall
Journal:  Can Med Assoc J       Date:  1984-06-01       Impact factor: 8.262

5.  Toxicity of tricyclic antidepressants--kinetics, mechanism, intervention: a review.

Authors:  S H Preskorn; H A Irwin
Journal:  J Clin Psychiatry       Date:  1982-04       Impact factor: 4.384

6.  Cardiovascular side effects of phenothiazines and tricyclic antidepressants. A review with precautionary measures.

Authors:  P A Lipscomb
Journal:  Postgrad Med       Date:  1980-03       Impact factor: 3.840

7.  The treatment of tricyclic antidepressant overdose with repeated charcoal.

Authors:  C M Swartz; A Sherman
Journal:  J Clin Psychopharmacol       Date:  1984-12       Impact factor: 3.153

8.  Fatal maprotiline intoxication.

Authors:  R A Curtis; N Giacona; D Burrows; J L Bauman; M Schaffer
Journal:  Drug Intell Clin Pharm       Date:  1984-09

9.  Electrophysiologic studies of perphenazine and protriptyline in a patient with psychotropic drug-induced ventricular fibrillation.

Authors:  R D Magorien; G M Jewell; S F Schaal; C V Leier
Journal:  Am J Med       Date:  1979-08       Impact factor: 4.965

10.  Poisoning with tricyclic and related antidepressants--a ten-year review.

Authors:  I R Starkey; A A Lawson
Journal:  Q J Med       Date:  1980
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