Literature DB >> 6427821

Chronic morphine-induced hyperactivity in rats is altered by nucleus accumbens and ventral tegmental lesions.

W C Bunney, V J Massari, A Pert.   

Abstract

Lesions of the nucleus accumbens (NA) and the ventral tegmental area (VTA) attenuated and delayed the onset of the locomotor excitatory effects of morphine following chronic administration. Neither lesion, however, totally prevented the increase in locomotor excitation. These findings suggest that while the NA and VTA seem to play a role in mediating the excitatory effects of morphine, other regions and brain circuits must also be involved.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6427821     DOI： 10.1007/bf00427677

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  14 in total

1.  Opiate receptor binding in rhesus monkey brain: association with limbic structures.

Authors:  C C LaMotte; A Snowman; C B Pert; S H Synder
Journal:  Brain Res       Date:  1978-10-27       Impact factor: 3.252

2.  Determination of methionine enkephalin in discrete regions of rat brain.

Authors:  J S Hong; H Y Yang; W Fratta; E Costa
Journal:  Brain Res       Date:  1977-10-07       Impact factor: 3.252

3.  Stimulant effects of enkephalin microinjection into the dopaminergic A10 area.

Authors:  C L Broekkamp; A G Phillips; A R Cools
Journal:  Nature       Date:  1979-04-05       Impact factor: 49.962

4.  Neuroanatomical focus for morphine and enkephalin-induced hypermotility.

Authors:  A Pert; C Sivit
Journal:  Nature       Date:  1977-02-17       Impact factor: 49.962

5.  Catecholamines in fetal and newborn rat brain.

Authors:  J T Coyle; D Henry
Journal:  J Neurochem       Date:  1973-07       Impact factor: 5.372

6.  Immunohistochemical localization of enkephalin in rat brain and spinal cord.

Authors:  M Sar; W E Stumpf; R J Miller; K J Chang; P Cuatrecasas
Journal:  J Comp Neurol       Date:  1978-11-01       Impact factor: 3.215

7.  Locomotor activation induced by infusion of endorphins into the ventral tegmental area: evidence for opiate-dopamine interactions.

Authors:  L Stinus; G F Koob; N Ling; F E Bloom; M Le Moal
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

8.  Differential effects of localized lesions of n. accumbens on morphine- and amphetamine-induced locomotor hyperactivity in the C57BL/6J mouse.

Authors:  H Teitelbaum; P Giammatteo; G A Mickley
Journal:  J Comp Physiol Psychol       Date:  1979-08

9.  Nucleus accumbens lesions reduce amphetamine hyperthermia but not hyperactivity.

Authors:  D Wirtshafter; K E Asin; E W Kent
Journal:  Eur J Pharmacol       Date:  1978-10-15       Impact factor: 4.432

10.  Biochemical mapping of the noradrenergic ventral bundle projection sites: evidence for a noradrenergic--dopaminergic interaction.

Authors:  T L O'Donohue; W R Crowley; D M Jacobowitz
Journal:  Brain Res       Date:  1979-08-17       Impact factor: 3.252
View more
  2 in total

1.  Reduced expression of the μ opioid receptor in some, but not all, brain regions in mice with OPRM1 A112G.

Authors:  Y-J Wang; P Huang; A Ung; J A Blendy; L-Y Liu-Chen
Journal:  Neuroscience       Date:  2012-01-03       Impact factor: 3.590

2.  Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPγS binding in mice with Oprm1 A112G.

Authors:  Yu-Jun Wang; Peng Huang; Julie A Blendy; Lee-Yuan Liu-Chen
Journal:  Addict Biol       Date:  2012-08-02       Impact factor: 4.280
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.