| Literature DB >> 479406 |
H Teitelbaum, P Giammatteo, G A Mickley.
Abstract
Mice of the C57BL/6J strain became hyperactive to increasing doses of morphine sulfate. This response was similar to locomotor hyperactivity induced by amphetamine. Lesions and chemical blockade of posterior n. accumbens abolished amphetamine-induced hyperactivity and reduced but did not abolish the morphine response. These experiments demonstrate that the response to the two drugs is mediated by overlapping but noncongruent neural systems.Entities:
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Year: 1979 PMID： 479406 DOI： 10.1037/h0077605
Source DB: PubMed Journal: J Comp Physiol Psychol ISSN： 0021-9940