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Literature DB >> 6427404

Non-A, non-B epidemic hepatitis: visualization of virus-like particles in the stool by immune electron microscopy.

M A Sreenivasan, V A Arankalle, A Sehgal, K M Pavri.

Abstract

Acute-phase stool samples collected from hepatitis cases during outbreaks of water-borne epidemic hepatitis were examined by immune electron microscopy (IEM). Spherical virus-like particles (27 nm in diameter) were visualized in the stool of a hepatitis patient with serological evidence of non-A, non-B (NANB) hepatitis. The IEM demonstrated serological specificity of the antigen with the patient's own convalescent serum as well as a known pool of NANB hepatitis convalescent sera. It is suggested that these virus-like particles may be the aetiological agent of faeco -orally transmitted NANB epidemic hepatitis in India.

Entities: Chemical Disease Species

Mesh：

Year: 1984 PMID： 6427404 DOI： 10.1099/0022-1317-65-5-1005

Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891

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Cited

12 in total

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Authors: J He; W M Ching; P Yarbough; H Wang; M Carl
Journal: J Clin Microbiol Date: 1995-12 Impact factor: 5.948

Review 3. Hepatitis E: Discovery, global impact, control and cure.

Authors: Mohammad S Khuroo; Mehnaaz S Khuroo; Naira S Khuroo
Journal: World J Gastroenterol Date: 2016-08-21 Impact factor: 5.742

4. Expression of a hepatitis E virus (HEV)-trpE fusion protein containing epitopes recognized by antibodies in sera from human cases and experimentally infected primates.

Authors: M A Purdy; K A McCaustland; K Krawczynski; A Tam; M J Beach; N C Tassopoulos; G R Reyes; D W Bradley
Journal: Arch Virol Date: 1992 Impact factor: 2.574

Non-A, non-B epidemic hepatitis: visualization of virus-like particles in the stool by immune electron microscopy.

Review 1. Lessons learned from successful human vaccines: Delineating key epitopes by dissecting the capsid proteins.

2. Purification of a baculovirus-expressed hepatitis E virus structural protein and utility in an enzyme-linked immunosorbent assay.

Review 3. Hepatitis E: Discovery, global impact, control and cure.

4. Expression of a hepatitis E virus (HEV)-trpE fusion protein containing epitopes recognized by antibodies in sera from human cases and experimentally infected primates.

5. Diagnosis of acute hepatitis E infection utilizing enzyme immunoassay.

6. Peek-a-boo: membrane hijacking and the pathogenesis of viral hepatitis.

7. Expression and diagnostic utility of hepatitis E virus putative structural proteins expressed in insect cells.

8. Expression of hepatitis E virus putative structural proteins in recombinant vaccinia viruses.

9. Biliary Secretion of Quasi-Enveloped Human Hepatitis A Virus.

10. Direct exposure of the head to solar heat radiation impairs motor-cognitive performance.