| Literature DB >> 6424465 |
B W Scheithauer, P C Carpenter, B Bloch, P Brazeau.
Abstract
Rarely, acromegaly is produced by neuroendocrine neoplasms elaborating a substance similar to or identical with growth hormone-releasing factor. This report reviews the cases described to date and presents the clinicopathologic features of a patient with acromegaly, mild sellar enlargement, and elevated growth hormone levels associated with a large bronchial carcinoid tumor. Normalization of serum growth hormone levels and regression of acromegaly followed resection of the bronchial tumor, which was shown, by bioassay and immunocytochemistry, to contain a growth hormone-releasing factor.Entities:
Mesh:
Substances:
Year: 1984 PMID: 6424465 DOI: 10.1016/0002-9343(84)90284-5
Source DB: PubMed Journal: Am J Med ISSN: 0002-9343 Impact factor: 4.965