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Literature DB >> 6422042

N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.

K Sestanj, F Bellini, S Fung, N Abraham, A Treasurywala, L Humber, N Simard-Duquesne, D Dvornik.

Abstract

Entities: Chemical Gene

Mesh：

Substances：

Year: 1984 PMID： 6422042 DOI： 10.1021/jm00369a003

Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446

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11 in total

1. Soft docking and multiple receptor conformations in virtual screening.

Authors: Anna Maria Ferrari; Binqing Q Wei; Luca Costantino; Brian K Shoichet
Journal: J Med Chem Date: 2004-10-07 Impact factor: 7.446

Review 2. The aldo-keto reductase superfamily and its role in drug metabolism and detoxification.

Authors: Oleg A Barski; Srinivas M Tipparaju; Aruni Bhatnagar
Journal: Drug Metab Rev Date: 2008 Impact factor: 4.518

3. Binding of aldose reductase inhibitors: correlation of crystallographic and mass spectrometric studies.

Authors: H Rogniaux; A Van Dorsselaer; P Barth; J F Biellmann; J Barbanton; M van Zandt; B Chevrier; E Howard; A Mitschler; N Potier; L Urzhumtseva; D Moras; A Podjarny
Journal: J Am Soc Mass Spectrom Date: 1999-07 Impact factor: 3.109

4. Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.

Authors: A Y Lee; S K Chung; S S Chung
Journal: Proc Natl Acad Sci U S A Date: 1995-03-28 Impact factor: 11.205

5. Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues.

Authors: Kun-Che Chang; Brian Laffin; Jessica Ponder; Anna Enzsöly; János Németh; Daniel V LaBarbera; J Mark Petrash
Journal: Chem Biol Interact Date: 2012-12-15 Impact factor: 5.192

Review 6. The aldo-keto reductases (AKRs): Overview.

Authors: Trevor M Penning
Journal: Chem Biol Interact Date: 2014-10-07 Impact factor: 5.192

7. Bioactivity Focus of α-Cyano-4-hydroxycinnamic acid (CHCA) Leads to Effective Multifunctional Aldose Reductase Inhibitors.

Authors: Laitao Zhang; Yi-Fang Li; Sheng Yuan; Shijie Zhang; Huanhuan Zheng; Jie Liu; Pinghua Sun; Yijun Gu; Hiroshi Kurihara; Rong-Rong He; Heru Chen
Journal: Sci Rep Date: 2016-04-25 Impact factor: 4.379