Literature DB >> 6420867

[A genetic form of petit mal absence in Wistar rats].

C Marescaux, M Vergnes, G Micheletti, A Depaulis, J Reis, L Rumbach, J M Warter, D Kurtz.   

Abstract

One-third of the Wistar rats bred in the Centre of Neurochemistry in Strasbourg, France, develop spontaneous epileptic seizures which from their clinical manifestations, pharmacological responses, and electroencephalographic findings are suggestive of Petit Mal absences. These fits are genetically determined since in two lines selected from affected animals they occurred in 90 p. cent of three generations. The selection of a pure strain should assist in the use of this pharmacologic and neurophysiologic model of Petit Mal epilepsy.

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Year:  1984        PMID： 6420867

Source DB:  PubMed          Journal:  Rev Neurol (Paris)        ISSN： 0035-3787            Impact factor:   2.607


  7 in total

1.  Genetics of absence epilepsy in rats.

Authors:  B W Peeters; J M Kerbusch; E L van Luijtelaar; J M Vossen; A M Coenen
Journal:  Behav Genet       Date:  1990-05       Impact factor: 2.805

2.  Pentylenetetrazol-induced spike wave discharges in rats: a polygraphic study.

Authors:  G Gallitto; R Musolino; G Aliquò; A Bruno; P De Domenico; C E Marlara; L Marabello; R M Puglisi; R Sturniolo; R Di Perri
Journal:  Ital J Neurol Sci       Date:  1987-04

3.  Genetics of spike-wave discharges in the electroencephalogram (EEG) of the WAG/Rij inbred rat strain: a classical mendelian crossbreeding study.

Authors:  B W Peeters; J M Kerbusch; A M Coenen; J M Vossen; E L van Luijtelaar
Journal:  Behav Genet       Date:  1992-05       Impact factor: 2.805

4.  Cellular and network mechanisms of genetically-determined absence seizures.

Authors:  Didier Pinault; Terence J O'Brien
Journal:  Thalamus Relat Syst       Date:  2007-01-22

5.  Blockade of "antiabsence" activity of sodium valproate by THIP in rats with petit mal-like seizures. Comparison with ethosuximide.

Authors:  M Vergnes; C Marescaux; G Micheletti; L Rumbach; J M Warter
Journal:  J Neural Transm       Date:  1985       Impact factor: 3.575

6.  Evaluating whole genome sequence data from the Genetic Absence Epilepsy Rat from Strasbourg and its related non-epileptic strain.

Authors:  Pablo M Casillas-Espinosa; Kim L Powell; Mingfu Zhu; C Ryan Campbell; Jessica M Maia; Zhong Ren; Nigel C Jones; Terence J O'Brien; Slavé Petrovski
Journal:  PLoS One       Date:  2017-07-14       Impact factor: 3.240

Review 7.  Establishing Drug Effects on Electrocorticographic Activity in a Genetic Absence Epilepsy Model: Advances and Pitfalls.

Authors:  Gilles van Luijtelaar; Gerard van Oijen
Journal:  Front Pharmacol       Date:  2020-04-14       Impact factor: 5.810
  7 in total

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