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Literature DB >> 6418770

Identification of cellular immunoglobulins in chronic lymphocytic leukaemia by immunoperoxidase staining.

G M Markey, R E McConnell, H D Alexander, T C Morris, J H Robertson.

Abstract

An indirect immunoperoxidase technique has been used for visualisation of cellular immunoglobulins in chronic lymphocytic leukaemia. Baker's formol calcium was used as fixative. Monoclonal light and heavy chain patterns were demonstrated in 24 out of 27 cases. Only one case did not have any demonstrable immunoglobulins. The presence of alpha or gamma heavy chain immunoglobulin isotypes in leukaemic lymphocytes was found to be related to low mouse rosetting capacity (p less than 0.05).

Entities: Chemical Disease Species

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Year: 1983 PMID： 6418770 PMCID： PMC498575 DOI： 10.1136/jcp.36.12.1391

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

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References

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Authors: G Laurent; M Gourdin; F Reyes
Journal: Am J Clin Pathol Date: 1980-09 Impact factor: 2.493

Identification of cellular immunoglobulins in chronic lymphocytic leukaemia by immunoperoxidase staining.

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