Literature DB >> 6418640

Isotype of antibodies responsible for immune lysis in Trypanosoma cruzi infected mice.

M M Stefani, H A Takehara, I Mota.   

Abstract

Serum obtained from mice infected with Trypanosoma cruzi have antibodies able to induce immune lysis in presence of complement. Gel filtration in Sephadex G-200 and affinity chromatography with rabbit anti-mouse IgG and protein A-Sepharose showed that the antibodies responsible for the immune serum lytic activity are exclusively located in Ig of IgG isotype, including IgG1, IgG2a, IgG2b and probably IgG3. It is suggested that antibodies responsible for protection against T. cruzi infection and antibodies responsible for immune lysis are the same.

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Year:  1983        PMID： 6418640     DOI： 10.1016/0165-2478(83)90040-8

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  3 in total

1.  Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice.

Authors:  E C Lima; I Garcia; M H Vicentelli; P Vassalli; P Minoprio
Journal:  Infect Immun       Date:  1997-02       Impact factor: 3.441

2.  IgG Subclass Analysis in Patients with Chagas Disease 4 Years After Benznidazole Treatment.

Authors:  Maurício Llaguno; Marcos Vinícius da Silva; Fernanda Rodrigues Helmo; Lara Rocha Batista; Djalma Alexandre Alves da Silva; Rodrigo Cunha de Sousa; Luiz Antonio Pertili Rodrigues de Resende; Eliane Lages-Silva; Carlo José Freire Oliveira; Juliana Reis Machado; Denise Bertulucci Rocha Rodrigues; Dalmo Correia; Virmondes Rodrigues
Journal:  Acta Parasitol       Date:  2021-06-11       Impact factor: 1.440

3.  Comparison of the C-mediating killing activity and C-activating properties of mouse monoclonal and polyclonal antibodies against Trypanosoma cruzi.

Authors:  T L Kipnis; D V Tambourgi; M J Alves; W D Silva
Journal:  Mediators Inflamm       Date:  1992       Impact factor: 4.711
  3 in total

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