Literature DB >> 6418066

Susceptibility of Mycobacterium tuberculosis to pyrazinamide and its relationship to pyrazinamidase activity.

W R Butler, J O Kilburn.   

Abstract

Pyrazinamidase activity has been associated with pyrazinamide-susceptible Mycobacterium tuberculosis strains. The detection of pyrazinamidase activity by the Wayne method was found to be of limited value when compared with the results of standard pyrazinamide susceptibility tests, especially when a high level of pyrazinamide resistance was found. When resistance to pyrazinamide reached a level of 150 to 200 micrograms/ml, there was too much variability in Wayne test results to accurately define pyrazinamide susceptibility.

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Year:  1983        PMID： 6418066      PMCID： PMC185381          DOI： 10.1128/AAC.24.4.600

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  8 in total

1.  Activation of pyrazinamide and nicotinamide in acidic environments in vitro.

Authors:  W McDERMOTT; R TOMPSETT
Journal:  Am Rev Tuberc       Date:  1954-10

2.  Pyrazinamide susceptibility and amidase activity of tubercle bacilli.

Authors:  K Konno; F M Feldmann; W McDermott
Journal:  Am Rev Respir Dis       Date:  1967-03

3.  [Sensitivity of tubercle bacilli to pyrazinamide determined on the basis of their sensitivity to nicotinamide and their pyrazinamidase and nictinamidase activities].

Authors:  J Tatar
Journal:  Gruzlica       Date:  1974-08

4.  A simple way of detecting pyrazinamide resistance.

Authors:  E Brander
Journal:  Tubercle       Date:  1972-06

5.  Determination of drug susceptibility of mycobacteria to pyrazinamide in 7H10 agar.

Authors:  K D Stottmeier; R E Beam; G P Kubica
Journal:  Am Rev Respir Dis       Date:  1967-11

6.  Simple pyrazinamidase and urease tests for routine identification of mycobacteria.

Authors:  L G Wayne
Journal:  Am Rev Respir Dis       Date:  1974-01

7.  Improved method for testing susceptibility of Mycobacterium tuberculosis to pyrazinamide.

Authors:  W R Butler; J O Kilburn
Journal:  J Clin Microbiol       Date:  1982-12       Impact factor: 5.948

8.  Use of pyrazinamidase activity on Mycobacterium tuberculosis as a rapid method for determination of pyrazinamide susceptibility.

Authors:  J K McClatchy; A Y Tsang; M S Cernich
Journal:  Antimicrob Agents Chemother       Date:  1981-10       Impact factor: 5.191
  8 in total
  26 in total

1.  Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis.

Authors:  M Mestdagh; P A Fonteyne; L Realini; R Rossau; G Jannes; W Mijs; K A De Smet; F Portaels; E Van den Eeckhout
Journal:  Antimicrob Agents Chemother       Date:  1999-09       Impact factor: 5.191

2.  Pyrazinoic acid efflux rate in Mycobacterium tuberculosis is a better proxy of pyrazinamide resistance.

Authors:  Mirko Zimic; Patricia Fuentes; Robert H Gilman; Andrés H Gutiérrez; Daniela Kirwan; Patricia Sheen
Journal:  Tuberculosis (Edinb)       Date:  2011-10-17       Impact factor: 3.131

Review 3.  The Bewildering Antitubercular Action of Pyrazinamide.

Authors:  Elise A Lamont; Nicholas A Dillon; Anthony D Baughn
Journal:  Microbiol Mol Biol Rev       Date:  2020-03-04       Impact factor: 11.056

4.  Rapid detection of pyrazinamide-resistant Mycobacterium tuberculosis by a PCR-based in vitro system.

Authors:  Yasuhiko Suzuki; Aya Suzuki; Aki Tamaru; Chihiro Katsukawa; Hajime Oda
Journal:  J Clin Microbiol       Date:  2002-02       Impact factor: 5.948

5.  New agar medium for testing susceptibility of Mycobacterium tuberculosis to pyrazinamide.

Authors:  L Heifets; T Sanchez
Journal:  J Clin Microbiol       Date:  2000-04       Impact factor: 5.948

6.  Testing of susceptibility of Mycobacterium tuberculosis to pyrazinamide: comparison of Bactec method with pyrazinamidase assay.

Authors:  M A Miller; L Thibert; F Desjardins; S H Siddiqi; A Dascal
Journal:  J Clin Microbiol       Date:  1995-09       Impact factor: 5.948

7.  Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis.

Authors:  Karolien Stoffels; Vanessa Mathys; Maryse Fauville-Dufaux; René Wintjens; Pablo Bifani
Journal:  Antimicrob Agents Chemother       Date:  2012-07-23       Impact factor: 5.191

8.  Improved Detection by Next-Generation Sequencing of Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates.

Authors:  Nontuthuko E Maningi; Luke T Daum; John D Rodriguez; Matsie Mphahlele; Remco P H Peters; Gerald W Fischer; James P Chambers; P Bernard Fourie
Journal:  J Clin Microbiol       Date:  2015-09-16       Impact factor: 5.948

9.  Radiometric method for testing susceptibility of mycobacteria to pyrazinamide in 7H12 broth.

Authors:  L B Heifets; M D Iseman
Journal:  J Clin Microbiol       Date:  1985-02       Impact factor: 5.948

10.  Activity of pyrazinamide in a murine model against Mycobacterium tuberculosis isolates with various levels of in vitro susceptibility.

Authors:  S P Klemens; C A Sharpe; M H Cynamon
Journal:  Antimicrob Agents Chemother       Date:  1996-01       Impact factor: 5.191
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