Literature DB >> 641805

Mathematical basis of point-area deconvolution method for determining in vivo input functions.

D P Vaughan, M Dennis.   

Abstract

The point-area method for deconvolution derives a "staircase" input function which, when convolved onto the characteristic function, gives an output function coincidental with the given output data points. The area--area method for deconvolution is shown to be erroneous.

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Year:  1978        PMID： 641805     DOI： 10.1002/jps.2600670524

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  56 in total

Review 1.  Measures of exposure versus measures of rate and extent of absorption.

Authors:  M L Chen; L Lesko; R L Williams
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

2.  In silico prediction of optimal in vivo delivery properties using convolution-based model and clinical trial simulation.

Authors:  Roberto Gomeni; Carla Dangeli; Alan Bye
Journal:  Pharm Res       Date:  2002-01       Impact factor: 4.200

3.  An extended point-area deconvolution approach for assessing drug input rates.

Authors:  K C Yeh; D J Holder; G A Winchell; L A Wenning; T Prueksaritanont
Journal:  Pharm Res       Date:  2001-10       Impact factor: 4.200

Review 4.  Pharmacokinetic characterization of controlled-release formulations.

Authors:  V W Steinijans
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1990 Apr-Jun       Impact factor: 2.441

Review 5.  Systems dynamics in clinical pharmacokinetics. An introduction.

Authors:  J M van Rossum; J E de Bie
Journal:  Clin Pharmacokinet       Date:  1989-07       Impact factor: 6.447

6.  Pharmacokinetic evaluation of stable piecewise cubic polynomials as numerical integration functions.

Authors:  K C Yeh; R D Small
Journal:  J Pharmacokinet Biopharm       Date:  1989-12

7.  The effect of age on the systemic absorption, disposition and pharmacodynamics of bupivacaine after epidural administration.

Authors:  B T Veering; A G Burm; A A Vletter; R P van den Heuvel; W Onkenhout; J Spierdijk
Journal:  Clin Pharmacokinet       Date:  1992-01       Impact factor: 6.447

8.  Pharmacokinetics and pharmacodynamics of a new transdermal delivery system for bopindolol.

Authors:  J Drewe; R Meier; U Timonen; M Thumshirn; J Munzer; T Kissel; K Gyr
Journal:  Br J Clin Pharmacol       Date:  1991-06       Impact factor: 4.335

9.  Mathematical model for in vivo pharmacodynamics integrating fluctuation of the response: application to the prolactin suppressant effect of the dopaminomimetic drug DCN 203-922.

Authors:  P Francheteau; J L Steimer; C Dubray; D Lavene
Journal:  J Pharmacokinet Biopharm       Date:  1991-06

10.  Pharmacokinetics of intranasally-administered dihydroergotamine in the rat.

Authors:  D T Lau; Z Yu; R L Aun; A E Hassell; F L Tse
Journal:  Pharm Res       Date:  1994-11       Impact factor: 4.200
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