| Literature DB >> 6414154 |
M Toro, E León, R López, F Pallota, J A Garcia, A Ruíz.
Abstract
Assays dealing with the therapeutic and prophylactic activity of isometamidium on experimental infections by Trypanosoma vivax and T. evansi were carried out. The drug was found to be highly effective against T. vivax infection in sheep and cattle in which periods of protection ranging from 118 to 195 days were achieved. No complete effects against infection by T. evansi were observed. The drug was well tolerated in sheep and cattle while side-effects were noted in treated mares. It was concluded that isometamidium could be used to prevent damage and economical losses caused by T. vivax in Venezuela.Entities:
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Year: 1983 PMID： 6414154 DOI： 10.1016/0304-4017(83)90018-3
Source DB: PubMed Journal: Vet Parasitol ISSN： 0304-4017 Impact factor: 2.738