Literature DB >> 6413850

Formaldehyde mutagenesis in Drosophila. Molecular analysis of ADH-negative mutants.

C Benyajati, A R Place, W Sofer.   

Abstract

The Adh gene from 4 formaldehyde-generated ADH-negative mutants of Drosophila melanogaster has been cloned and sequenced. All 4 mutants bear small deletions within the gene, ranging in size from 6 to 34 base pairs. 2 of the deletions lie within a 65-base pair intervening sequence and are accompanied by other aberrations. The other two are within the protein coding region of the gene. Some of these aberrations may be explained by a slipped mispairing mechanism.

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Year:  1983        PMID: 6413850     DOI: 10.1016/0027-5107(83)90002-7

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  14 in total

1.  Smg1 nonsense mutations do not abolish nonsense-mediated mRNA decay in Drosophila melanogaster.

Authors:  Zhenzhong Chen; Katherine R Smith; Philip Batterham; Charles Robin
Journal:  Genetics       Date:  2005-06-18       Impact factor: 4.562

2.  The partial characterization of alcohol dehydrogenase null alleles from natural populations of Drosophila melanogaster.

Authors:  A L Freeth; J B Gibson; H G de Couet
Journal:  Biochem Genet       Date:  1986-12       Impact factor: 1.890

3.  Analysis of sequences regulating larval expression of the Adh gene of Drosophila melanogaster.

Authors:  N L Shen; E C Hotaling; G Subrahmanyam; P F Martin; W Sofer
Journal:  Genetics       Date:  1991-11       Impact factor: 4.562

4.  Molecular consequences of two formaldehyde-induced mutations in the alcohol dehydrogenase gene of Drosophila melanogaster.

Authors:  A R Place; C Benyajati; W Sofer
Journal:  Biochem Genet       Date:  1987-10       Impact factor: 1.890

5.  Conversion and reciprocal exchange between tandem repeats in Drosophila melanogaster.

Authors:  R Hipeau-Jacquotte; D L Brutlag; F Brégégère
Journal:  Mol Gen Genet       Date:  1989-12

6.  Inducible transcription and puffing in Drosophila melanogaster transformed with hsp70-phage lambda hybrid heat shock genes.

Authors:  R S Cohen; M Meselson
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

7.  Compensatory evolution of a precursor messenger RNA secondary structure in the Drosophila melanogaster Adh gene.

Authors:  Ying Chen; Wolfgang Stephan
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-12       Impact factor: 11.205

8.  Interactions between the regulatory regions of two Adh alleles.

Authors:  R Freidman; E Hotaling; L Borack; W Sofer
Journal:  Genetica       Date:  1996-01       Impact factor: 1.082

9.  The cross-linking agent hexamethylphosphoramide predominantly induces intra-locus and multi-locus deletions in postmeiotic germ cells of Drosophila.

Authors:  I Aguirrezabalaga; M J Nivard; M A Comendador; E W Vogel
Journal:  Genetics       Date:  1995-02       Impact factor: 4.562

10.  A Drosophila Adh gene can be activated in trans by an enhancer.

Authors:  I Rothberg; E Hotaling; W Sofer
Journal:  Nucleic Acids Res       Date:  1991-10-25       Impact factor: 16.971

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