Anaesthesia for laparoscopy: alfentanil and fentanyl compared.

A double blind comparison was made between alfentanil and fentanyl as analgesic components of anaesthesia. Sixty-six women undergoing laparoscopy received methohexitone, alcuronium, nitrous oxide and oxygen, with either alfentanil 0.75 mg or fentanyl 0.25 mg. Ten of the patients who received alfentanil and 1 patient who received fentanyl required supplementation of anaesthesia by enflurane. Recovery from anaesthesia was similar in the two groups of patients though the onset of spontaneous breathing occurred more quickly after alfentanil (P less than 0.002). The injection of fentanyl was followed by a fall in BP (P less than 0.05) and the mean minimum value for pulse rate occurring after fentanyl was slower than after alfentanil (P less than 0.05).

RCT Entities:   Population Interventions Outcomes