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Literature DB >> 6411687

Sequence-specific DNA modification in Neisseria gonorrhoeae.

Abstract

Neisseria gonorrhoeae 82409/55(pJD1) is postulated to possess six DNA sequence-specific cytosine methyltransferases and one DNA sequence-specific N6-adenine methyltransferase. From the DNA sequencing of the plasmid pJD1 (manuscript in preparation) by a modification of the Maxam and Gilbert chemical cleavage procedure, the cytosine methylation specificities were demonstrated. Five of these methylating enzymes and their respective specificities are M . NgoI (formula; see text) does not methylate the cytosine of its recognition sequence, in agreement with a detected adenine modification. A biological implication of these different DNA methylating activities is discussed.

Entities: Chemical Species

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Year: 1983 PMID： 6411687 PMCID： PMC217831 DOI： 10.1128/jb.155.3.1324-1332.1983

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

13 in total

6. The Neisseria gonorrhoeae S.NgoVIII restriction/modification system: a type IIs system homologous to the Haemophilus parahaemolyticus HphI restriction/modification system.

Authors: J S Gunn; D C Stein
Journal: Nucleic Acids Res Date: 1997-10-15 Impact factor: 16.971

7. Use of a non-selective transformation technique to construct a multiply restriction/modification-deficient mutant of Neisseria gonorrhoeae.

Authors: J S Gunn; D C Stein
Journal: Mol Gen Genet Date: 1996-07-19

Sequence-specific DNA modification in Neisseria gonorrhoeae.

1. Genetic basis for colonial variation in Neisseria gonorrhoeae.

2. Identification of a new sequence-specific endonuclease, NgoII, from Neisseria gonorrhoeae.

3. Replicational fidelity: mechanisms of mutation avoidance and mutation fixation.

4. Detection of 5-methylcytosine in DNA sequences.

5. A simple method for DNA restriction site mapping.

Review 6. Structure and mechanism of multifunctional restriction endonucleases.

7. Restriction and modification enzymes and their recognition sequences.

8. Sequencing end-labeled DNA with base-specific chemical cleavages.

9. Specificity of Hpa II and Hae III DNA methylases.

10. Deoxyribonucleic acid modifications and restriction endonuclease production in Neisseria gonorrhoeae.

1. Cloning and linkage analysis of Neisseria gonorrhoeae DNA methyltransferases.

2. Effect of site-specific methylation on DNA modification methyltransferases and restriction endonucleases.

3. Restriction of plasmid DNA during transformation but not conjugation in Neisseria gonorrhoeae.

4. DNA methylation in leprosy-associated bacteria: Mycobacterium leprae and Corynebacterium tuberculostearicum.

5. Site-specific methylation: effect on DNA modification methyltransferases and restriction endonucleases.

6. The Neisseria gonorrhoeae S.NgoVIII restriction/modification system: a type IIs system homologous to the Haemophilus parahaemolyticus HphI restriction/modification system.

7. Use of a non-selective transformation technique to construct a multiply restriction/modification-deficient mutant of Neisseria gonorrhoeae.

8. Intragenic variation by site-specific recombination in the cryptic plasmid of Neisseria gonorrhoeae.

Review 9. The effect of site-specific methylation on restriction-modification enzymes.

10. Two unique restriction endonucleases from Neisseria lactamica.