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Literature DB >> 6409814

Action of different gamma interferons on mouse leukemic cells resistant to alpha and beta interferons.

F Besançon, J Wietzerbin, S Stefanos, J Wietzerbin, E Falcoff.

Abstract

Phytohemagglutinin-induced interferon-gamma (IFN-gamma) was reported to act on mouse leukemic L1210 R cells resistant to IFN-alpha and -beta. Results reported here show that these cells are also sensitive to various preparations of murine IFN-gamma derived from different sources and purified to different degrees and that lymphokines present in the preparations are not involved in the antiviral effect of IFN. In addition, IFN-gamma preparation increases concanavalin A binding to L1210 S and L1210 R cells indicating that the sensitivity of L1210 R cells to IFN-gamma is not limited to its antiviral effect.

Entities: Disease Gene Mutation Species

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Year: 1983 PMID： 6409814 PMCID： PMC264713 DOI： 10.1128/iai.41.2.822-825.1983

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

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References

17 in total

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Journal: Nature Date: 1976-02-19 Impact factor: 49.962

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Authors: J S Youngner; S B Salvin
Journal: J Immunol Date: 1973-12 Impact factor: 5.422

Action of different gamma interferons on mouse leukemic cells resistant to alpha and beta interferons.

1. Specificity and reversibility of interferon ganglioside interaction.

2. Correlation between the antiviral effect of interferon treatment and the inhibition of in vitro mRNA translation in noninfected L cells.

3. Production and properties of migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity.

4. Interferon and cell division. IX. Interferon-resistant L1210 cells: characteristics and origin.

5. Interferon nomenclature.

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9. Binding of 125I-labelled human alpha interferon to human lymphoid cells.

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