Literature DB >> 43358

Physico-chemical characterization and partial purification of mouse immune interferon.

J Wietzerbin, S Stefanos, M Lucero, E Falcoff, J A O'Malley, E Sulkowski.   

Abstract

Mouse immune (type T) interferon was produced from suspensions of spleen cells (1 X 10(7) cells/ml) treated with 3 micrograms/ml of phytohaemagglutinin. The crude interferon was chromatographed on four sorbents with varying affinities, namely concanavalin A-Sepharose, Affi-Gel 202, Blue Sepharose CL-6B and Phenyl-Sepharose CL-4B. With each of these the interferon activity was observed to have considerable heterogeneity. By means of affinity chromatography, mouse immune interferon was purified 100 to 200 times with concomitant complete recovery of activity.

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Year:  1979        PMID： 43358     DOI： 10.1099/0022-1317-44-3-773

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  10 in total

1.  The glycoprotein nature of murine gamma interferon.

Authors:  E A Havell; G L Spitalny
Journal:  Arch Virol       Date:  1984       Impact factor: 2.574

2.  Intracellular human gamma-interferon triggers an antiviral state in transformed murine L cells.

Authors:  J Sancéau; P Sondermeyer; F Béranger; R Falcoff; C Vaquero
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

3.  Monoclonal antibodies against murine gamma interferon.

Authors:  M Prat; G Gribaudo; P M Comoglio; G Cavallo; S Landolfo
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

4.  The recruitment of lymphocytes into the skin by T cell lymphokines: the role of gamma-interferon.

Authors:  T B Issekutz; J M Stoltz; P van der Meide
Journal:  Clin Exp Immunol       Date:  1988-07       Impact factor: 4.330

5.  Spontaneous production of gamma interferon and induced production of beta interferon by human T-lymphoblastoid cell lines.

Authors:  A G Morris; J Morser; A Meager
Journal:  Infect Immun       Date:  1982-02       Impact factor: 3.441

6.  Studies on Brucella interferon: chromatographic behaviour and purification.

Authors:  C Bousquet-Ucla; J Wietzerbin; E Falcoff
Journal:  Arch Virol       Date:  1980       Impact factor: 2.574

7.  Cloning and expression of murine immune interferon cDNA.

Authors:  P W Gray; D V Goeddel
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

8.  Action of different gamma interferons on mouse leukemic cells resistant to alpha and beta interferons.

Authors:  F Besançon; J Wietzerbin; S Stefanos; J Wietzerbin; E Falcoff
Journal:  Infect Immun       Date:  1983-08       Impact factor: 3.441

9.  Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities.

Authors:  G L Spitalny; E A Havell
Journal:  J Exp Med       Date:  1984-05-01       Impact factor: 14.307

10.  Enhanced production of murine interferon gamma by T cells generated in response to bacterial infection.

Authors:  E A Havell; G L Spitalny; P J Patel
Journal:  J Exp Med       Date:  1982-07-01       Impact factor: 14.307
  10 in total

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