Literature DB >> 6409356

Facilitation of neocortical kindling by depletion of forebrain noradrenaline.

I M Altman, M E Corcoran.   

Abstract

The role of forebrain noradrenaline in seizures induced by electrical stimulation of the anterior neocortex (kindling) was investigated in control rats and rats pretreated with bilateral injections of 6-hydroxydopamine (6-OHDA) into the mesencephalic trajectory of the dorsal tegmental noradrenergic bundle. Extensive depletion of forebrain noradrenaline significantly facilitated the rate of development of cortico-generalized seizures.

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Year:  1983        PMID： 6409356     DOI： 10.1016/0006-8993(83)90810-7

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  6 in total

1.  Mechanisms of epileptic brain damage: evidence for a protective role of the noradrenergic locus coeruleus system in the rat.

Authors:  G Nevander; M Ingvar; O Lindvall
Journal:  Exp Brain Res       Date:  1986       Impact factor: 1.972

2.  Supersensitivity to the anticonvulsant and proconvulsant activity of clonidine following noradrenaline depletion induced by 6-hydroxydopamine.

Authors:  J C Dalton; D C Roberts; D C McIntyre
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

3.  Seizure suppression in kindling epilepsy by intracerebral implants of GABA- but not by noradrenaline-releasing polymer matrices.

Authors:  M Kokaia; P Aebischer; E Elmér; J Bengzon; P Kalén; Z Kokaia; O Lindvall
Journal:  Exp Brain Res       Date:  1994       Impact factor: 1.972

Review 4.  Pharmacological effects of phenylalanine on seizure susceptibility: an overview.

Authors:  P Y Sze
Journal:  Neurochem Res       Date:  1989-02       Impact factor: 3.996

5.  Mechanisms of Psychiatric Comorbidities in Epilepsy.

Authors:  Jamie Maguire
Journal:  Curr Top Behav Neurosci       Date:  2022

6.  Norepinephrine Protects against Methamphetamine Toxicity through β2-Adrenergic Receptors Promoting LC3 Compartmentalization.

Authors:  Gloria Lazzeri; Carla L Busceti; Francesca Biagioni; Cinzia Fabrizi; Gabriele Morucci; Filippo S Giorgi; Michela Ferrucci; Paola Lenzi; Stefano Puglisi-Allegra; Francesco Fornai
Journal:  Int J Mol Sci       Date:  2021-07-05       Impact factor: 5.923
  6 in total

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