Literature DB >> 640273

Hormone-sensitive adenylate cyclase in human colonic mucosa.

B Simon, P Czygan, G Spaan, J Dittrich, H Kather.   

Abstract

Human colonic adenylate cyclase has been shown to be sensitive to vasoactive intestinal polypeptide (VIP) and prostaglandins of the E- and F-type. Maximal activation of enzyme activity averaged 200% for VIP and 300-350% for the E-prostaglandins. Both classes of hormones had an additive effect on enzyme activity indicating the existence of two distinct hormone-sensitive adenylate cyclases in human colonic mucosa.

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Year:  1978        PMID： 640273     DOI： 10.1159/000198114

Source DB:  PubMed          Journal:  Digestion        ISSN： 0012-2823            Impact factor:   3.216


  5 in total

1.  Laxatives and human colonic mucosal cyclic AMP.

Authors:  B Simon; H Kather
Journal:  Dig Dis Sci       Date:  1980-02       Impact factor: 3.199

2.  Effects of bisacodyl on cAMP and prostaglandin E2 contents, (Na + K) ATPase, adenyl cyclase, and phosphodiesterase activities of rat intestine.

Authors:  D Rachmilewitz; F Karmeli; E Okon
Journal:  Dig Dis Sci       Date:  1980-08       Impact factor: 3.199

3.  Effect of prostaglandin on ion transport across isolated colonic mucosa.

Authors:  L C Racusen; H J Binder
Journal:  Dig Dis Sci       Date:  1980-12       Impact factor: 3.199

4.  Effects of vasoactive intestinal peptide and pancreatic polypeptide in rabbit intestine.

Authors:  M Camilleri; B T Cooper; T E Adrian; S R Bloom; V S Chadwick
Journal:  Gut       Date:  1981-01       Impact factor: 23.059

5.  Peptide histidine isoleucine: a secretagogue in human jejunum.

Authors:  A A Anagnostides; N D Christofides; K Tatemoto; V S Chadwick; S R Bloom
Journal:  Gut       Date:  1984-04       Impact factor: 23.059
  5 in total

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