Literature DB >> 6401108

Solution NMR studies of intact lambda repressor.

M A Weiss1, M Karplus, D J Patel, R T Sauer.   

Abstract

Using a combination of two and one-dimensional NMR spectroscopy, it is shown that in the intact bacteriophage lambda repressor, the N-terminal domain assumes the same global structure as when it remains isolated. It is further shown that the N-terminal domain is only loosely attached to the C-terminal domain in the intact repressor.

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Year:  1983        PMID： 6401108     DOI： 10.1080/07391102.1983.10507431

Source DB:  PubMed          Journal:  J Biomol Struct Dyn        ISSN： 0739-1102


  7 in total

1.  NH2-terminal arm of phage lambda repressor contributes energy and specificity to repressor binding and determines the effects of operator mutations.

Authors:  J L Eliason; M A Weiss; M Ptashne
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

2.  Structure of proteins with single-site mutations: a minimum perturbation approach.

Authors:  H H Shih; J Brady; M Karplus
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

3.  A variant of lambda repressor with an altered pattern of cooperative binding to DNA sites.

Authors:  A Astromoff; M Ptashne
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-29       Impact factor: 11.205

4.  Effect of single amino acid replacements on the thermal stability of the NH2-terminal domain of phage lambda repressor.

Authors:  M H Hecht; J M Sturtevant; R T Sauer
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

5.  Dynamic filtering by two-dimensional 1H NMR with application to phage lambda repressor.

Authors:  M A Weiss; J L Eliason; D J States
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

6.  Isotope-detected 1H NMR studies of proteins: a general strategy for editing interproton nuclear Overhauser effects by heteronuclear decoupling, with application to phage lambda repressor.

Authors:  M A Weiss; A G Redfield; R H Griffey
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

7.  Variation of half-site organization and DNA looping by AraC protein.

Authors:  J H Carra; R F Schleif
Journal:  EMBO J       Date:  1993-01       Impact factor: 11.598
  7 in total

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