Literature DB >> 639951

Effect of theophylline on myocardial adenylate cyclase activity.

E Kruse, H Scholz.   

Abstract

Theophylline (0.001-10.0 mM) did not increase but rather decrased adenylate cyclase activity (AC) of guinea-pig auricles. Isoprenaline (1-100 microgram) and sodium fluoride (0.3-10.0 mM) stimulated AC in a concentration-dependent manner.

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Year:  1978        PMID： 639951     DOI： 10.1007/BF01935956

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Beta-adrenergic receptors in guinea-pig myocardial tissue.

Authors:  W Krawietz; D Poppert; E Erdmann; H Glossmann; C J Struck; C Konrad
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976-12       Impact factor: 3.000

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Effectiveness of theophylline to increase cyclic AMP levels and force of contraction in electrically paced guinea-pig auricles. Comparison with isoprenaline, calcium and ouabain.

Authors:  C Dönges; M Heitmann; H Jungbluth; T Meinertz; B Schmelzle; H Scholz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-12       Impact factor: 3.000

4.  Influence of cyclization and acyl substitution on the inotropic effects of adenine nucleotides.

Authors:  T Meinertz; H Nawrath; H Scholz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

5.  [Inhibition of adenyl cyclase preparations from rat kidney by calcium ions and various diuretics].

Authors:  K H Jakobs; K Schultz; G Schultz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000

6.  Sensitive determination for adenylate cyclase activity by cyclic adenosine 3',5'-monophosphate protein binding assay.

Authors:  U Schwabe; R Elbert; P S Schönhöfer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

7.  Preparation and characterization of adenylate cyclase from heart and skeletal muscle.

Authors:  G I Drummond; D L Severson
Journal:  Methods Enzymol       Date:  1974       Impact factor: 1.600

8.  Inhibition of norepinephrine stimulated adenyl cyclase by theophylline.

Authors:  H Sheppard
Journal:  Nature       Date:  1970-11-07       Impact factor: 49.962

9.  A protein binding assay for adenosine 3':5'-cyclic monophosphate.

Authors:  A G Gilman
Journal:  Proc Natl Acad Sci U S A       Date:  1970-09       Impact factor: 11.205

10.  Studies on the conditions for cyclic AMP formation in homogenised and intact fat cells by use of 3 H-ATP and 3 H-adenine.

Authors:  P S Schönhöfer; I F Skidmore
Journal:  Pharmacology       Date:  1971       Impact factor: 2.547
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  4 in total

1.  Effects of vanadate on the c-AMP system of the heart.

Authors:  W Schmitz; I Hackbarth; H Scholz; E Wetzel
Journal:  Basic Res Cardiol       Date:  1980 May-Jun       Impact factor: 17.165

2.  Evidence for adenosine receptor-mediated isoprenaline-antagonistic effects of the adenosine analogs PIA and NECA on force of contraction in guinea-pig atrial and ventricular cardiac preparations.

Authors:  M Böhm; R Brückner; W Meyer; M Nose; W Schmitz; H Scholz; J Starbatty
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-11       Impact factor: 3.000

3.  Effects of adenosine and adenosine-analogs on adenylate cyclase activity in the rat adipocyte plasma membrane: comparison of the properties of the enzyme with Mn2+ and Mg2+ as divalent cations.

Authors:  J de Vente; J Zaagsma
Journal:  Mol Cell Biochem       Date:  1981-10-30       Impact factor: 3.396

4.  Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts.

Authors:  T Bethke; D Brunkhorst; H von der Leyen; W Meyer; R Nigbur; H Scholz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-05       Impact factor: 3.000
  4 in total

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