| Literature DB >> 63953 |
C Chezzi, G Dettori, V Manzari, A M Aglianò, A Sanna.
Abstract
Complexes of high-molecular-weight RNA and reverse transcriptase (RNA-dependent DNA nucleotidyltransferase) have been detected in 14(77.8%) of 18 spleen from patients with Hodgkin's disease and in all samples tested of peripheral leukocytes and spleens from leukemic patients. The enzyme and its template are localized in a particle having a density between 1.16 and 1.19 g/ml. These observations describe characteristic features of RNA tumor viruses.Entities:
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Year: 1976 PMID: 63953 PMCID: PMC431581 DOI: 10.1073/pnas.73.12.4649
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205