Literature DB >> 4131745

Primate RNA tumor virus-like DNA synthesized endogenously by RNA-dependent DNA polymerase in virus-like particles from fresh human acute leukemic blood cells.

R C Gallo, N R Miller, W C Saxinger, D Gillespie.   

Abstract

A particle of discrete biochemical composition was purified from fresh, unfrozen peripheral blood leukocytes of human patients with acute myeloblastic leukemia. This particle endogenously synthesized DNA by use of an RNA primer and template. About half of the DNA sequences synthesized in the presence of actinomycin D hybridized to RNA isolated from type-C sarcoma viruses of primates or mice; lower annealing values were obtained with RNA isolated from other sarcoma or leukemia viruses. The results confirm and extend previous results from molecular hybridization experiments related to the existence in human leukemia of components of RNA tumor viruses.

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Year:  1973        PMID： 4131745      PMCID： PMC427204          DOI： 10.1073/pnas.70.11.3219

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  Nucleic acid hybridization with RNA immobilized on filter paper.

Authors:  W C Saxinger; C Ponnamperuma; D Gillespie
Journal:  Proc Natl Acad Sci U S A       Date:  1972-10       Impact factor: 11.205

2.  DNA-dependent DNA polymerases I and II from normal human-blood lymphocytes.

Authors:  R G Smith; R C Gallo
Journal:  Proc Natl Acad Sci U S A       Date:  1972-10       Impact factor: 11.205

3.  Murine sarcoma and leukemia viruses: genetic differences determined by RNA-DNA hybridization.

Authors:  J R Stephenson; S A Aaronson
Journal:  Virology       Date:  1971-11       Impact factor: 3.616

4.  Simultaneous detection of reverse transcriptase and high molecular weight RNA unique to oncogenic RNA viruses.

Authors:  J Schlom; S Spiegelman
Journal:  Science       Date:  1971-11-19       Impact factor: 47.728

5.  Viral and cellular DNA polymerase: comparison of activities with synthetic and natural RNA templates.

Authors:  M S Robert; R G Smith; R C Gallo; P S Sarin; J W Abrell
Journal:  Science       Date:  1972-05-19       Impact factor: 47.728

6.  Precipitation of nucleic acids with cetyltrimethylammonium bromide: a method for preparing viral and cellular DNA polymerase products for cesium sulfate density gradient analysis.

Authors:  M S Reitz; J W Abrell; C D Trainor; R C Gallo
Journal:  Biochem Biophys Res Commun       Date:  1972-10-06       Impact factor: 3.575

7.  Reverse transcriptase activity of human acute leukaemic cells: purification of the enzyme, response to AMV 70S RNA, and characterization of the DNA product.

Authors:  M G Sarngadharan; P S Sarin; M S Reitz; R C Gallo
Journal:  Nat New Biol       Date:  1972-11-15

8.  Human leukaemic cells contain reverse transcriptase associated with a high molecular weight virus-related RNA.

Authors:  W Baxt; R Hehlmann; S Spiegelman
Journal:  Nat New Biol       Date:  1972-11-15

9.  Electrophoretic separation of viral nucleic acids on polyacrylamide gels.

Authors:  D H Bishop; J R Claybrook; S Spiegelman
Journal:  J Mol Biol       Date:  1967-06-28       Impact factor: 5.469

10.  RNA in human leukemic cells related to the RNA of a mouse leukemia virus (leukocytes-RNA-DNA hybridization-rauscher virus-polysomal RNA).

Authors:  R Hehlmann; D Kufe; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1972-02       Impact factor: 11.205
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  27 in total

1.  Viral-related information in oncornavirus-lik particles isolated from cultures of marrow cells from leukemic patients in relapse and remission.

Authors:  T W Mak; S Kurtz; J Manaster; D Housman
Journal:  Proc Natl Acad Sci U S A       Date:  1975-02       Impact factor: 11.205

Review 2.  [Leukemia viruses].

Authors:  R Hehlmann
Journal:  Blut       Date:  1976-05

3.  Human antibodies reactive with purified envelope antigens of primate type C tumor viruses.

Authors:  R Kurth; U Mikschy
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

4.  Low frequency of (5'-3') -C-G- connection in 70S RNA from simian sarcoma virus.

Authors:  K Ohe; L B Oppenheim
Journal:  J Virol       Date:  1975-09       Impact factor: 5.103

5.  Transformation of cultured human embryonic fibroblasts by oncornavirus-like particles released from a human carcinoma cell line.

Authors:  H Balabanova; M Kotler; Y Becker
Journal:  Proc Natl Acad Sci U S A       Date:  1975-07       Impact factor: 11.205

6.  Oncornavirus-like particles from cultured bone marrow cells preceding leukemia and malignant histiocytosis.

Authors:  G J Vosika; W Krivit; J M Gerrard; P F Coccia; M E Nesbit; J J Coalson; B J Kennedy
Journal:  Proc Natl Acad Sci U S A       Date:  1975-07       Impact factor: 11.205

7.  Primate type-C virus nucleic acid sequences (woolly monkey and baboon types) in tissues from a patient with acute myelogenous leukemia and in viruses isolated from cultured cells of the same patient.

Authors:  M S Reitz; N R Miller; F Wong-Staal; R E Gallagher; R C Gallo; D H Gillespie
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

8.  Sequences present in both human leukemic cell nuclear DNA and Rauscher leukemia virus.

Authors:  W G Baxt
Journal:  Proc Natl Acad Sci U S A       Date:  1974-07       Impact factor: 11.205

9.  Evidence of particle-associated RNA-directed DNA polymerase and high molecular weight RNA in human gastrointestinal and lung malignancies.

Authors:  W Cuatico; J R Cho; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1974-08       Impact factor: 11.205

10.  Systematics of RNA tumor viruses and virus-like particles of human origin.

Authors:  N R Miller; W C Saxinger; M S Reitz; R E Gallagher; A M Wu; R C Gallo; D Gillespie
Journal:  Proc Natl Acad Sci U S A       Date:  1974-08       Impact factor: 11.205
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