Literature DB >> 6386694

A comparison of oxytetracycline and trimethoprim in the treatment of Chlamydia trachomatis urethritis.

P B Nielsen, J D Christensen, G Frentz.   

Abstract

The effect of trimethoprim was compared with that of oxytetracycline in the treatment of uncomplicated urethritis and/or cervicitis. Twenty-six patients treated with oxytetracycline were all microbiologically cured. Of 19 patients treated with trimethoprim, ten (53%) still harboured the chlamydia after two weeks. The superiority of tetracycline was even more pronounced following the evaluation of dysuria and discharges. 85% of the patients treated with oxytetracycline and 6% of those treated with trimethoprim had neither dysuria nor discharge after the completion of treatment. The patients who failed to be cured by trimethoprim were all successfully treated with oxytetracycline.

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Year:  1984        PMID: 6386694     DOI: 10.1007/bf01645960

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  14 in total

1.  Are chlamydial infections the most prevalent venereal disease?

Authors:  J Schachter; L Hanna; E C Hill; S Massad; C W Sheppard; J E Conte; S N Cohen; K F Meyer
Journal:  JAMA       Date:  1975-03-24       Impact factor: 56.272

2.  Trimethoprim in human prostatic tissue and prostatic fluid.

Authors:  M L Nielsen; I Hansen
Journal:  Scand J Urol Nephrol       Date:  1972

3.  The concentration of trimethoprim in prostatic fluid: nonionic diffusion or active transport?

Authors:  T A Stamey; S R Bushby; J Bragonje
Journal:  J Infect Dis       Date:  1973-11       Impact factor: 5.226

4.  Inhibition by pyrimidine analogues of the synthesis of folic acid by trachoma agents.

Authors:  P Reeve; J Taverne; S R Bushby
Journal:  J Hyg (Lond)       Date:  1968-06

5.  The effect of antibiotics on the growth of TRIC agents in embryonated eggs.

Authors:  M L Tarizzo; B Nabli
Journal:  Am J Ophthalmol       Date:  1967-05       Impact factor: 5.258

6.  Chemotherapy in bubonic lymphogranuloma venereum: a clinical and serological evaluation.

Authors:  A B GREAVES; M R HILLEMAN; S R TAGGART; A B BANKHEAD; M FELD
Journal:  Bull World Health Organ       Date:  1957       Impact factor: 9.408

7.  Activity of trimethoprim-sulfamethoxazole against Chlamydia trachomatis in vitro.

Authors:  M R Hammerschlag
Journal:  Rev Infect Dis       Date:  1982 Mar-Apr

8.  Persistence of chlamydial infection after treatment for neonatal conjunctivitis.

Authors:  E Rees; I A Tait; D Hobson; P Karayiannis; N Lee
Journal:  Arch Dis Child       Date:  1981-03       Impact factor: 3.791

9.  Treatment of nongonococcal urethritis with trimethoprim-sulphadiazine and with placebo. A double-blind partner-controlled study.

Authors:  J Paavonen; M Kousa; P Saikku; E Vartiainen; L Kanerva; A Lassus
Journal:  Br J Vener Dis       Date:  1980-04

10.  The antimicrobial susceptibility of Chlamydia trachomatis in cell culture.

Authors:  G L Ridgway; J M Owen; J D Oriel
Journal:  Br J Vener Dis       Date:  1978-04
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  1 in total

1.  Periodic health examination, 1996 update: 2. Screening for chlamydial infections. Canadian Task Force on the Periodic Health Examination.

Authors:  H D Davies; E E Wang
Journal:  CMAJ       Date:  1996-06-01       Impact factor: 8.262

  1 in total

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