Literature DB >> 6383213

Enzyme engineering.

W H Rastetter.   

Abstract

Enzyme research and development efforts have been shaped by the tools and concepts available for enzyme production and utilization. A new phase of enzymology characterized by the production of modified protein catalysts has begun, made possible by recombinant DNA technology.

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Year:  1983        PMID： 6383213     DOI： 10.1007/bf02779915

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN： 0273-2289            Impact factor:   2.926


  20 in total

1.  A three-dimensional model of the myoglobin molecule obtained by x-ray analysis.

Authors:  J C KENDREW; G BODO; H M DINTZIS; R G PARRISH; H WYCKOFF; D C PHILLIPS
Journal:  Nature       Date:  1958-03-08       Impact factor: 49.962

2.  The disulphide bonds of insulin.

Authors:  A P RYLE; F SANGER; L F SMITH; R KITAI
Journal:  Biochem J       Date:  1955-08       Impact factor: 3.857

3.  The reactivity of thiol-subtilisin, an enzyme containing a synthetic functional group.

Authors:  L Polgar; M L Bender
Journal:  Biochemistry       Date:  1967-02       Impact factor: 3.162

4.  Efficient correction of a mutation by use of chemically synthesized DNA.

Authors:  A Razin; T Hirose; K Itakura; A D Riggs
Journal:  Proc Natl Acad Sci U S A       Date:  1978-09       Impact factor: 11.205

5.  Enzymatic replacement of the arginyl by a lysyl residue in the reactive site of soybean trypsin inhibitor.

Authors:  R W Sealock; M Laskowski
Journal:  Biochemistry       Date:  1969-09       Impact factor: 3.162

6.  Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding.

Authors:  G Winter; A R Fersht; A J Wilkinson; M Zoller; M Smith
Journal:  Nature       Date:  1982-10-21       Impact factor: 49.962

7.  Real-time color graphics in studies of molecular interactions.

Authors:  R Langridge; T E Ferrin; I D Kuntz; M L Connolly
Journal:  Science       Date:  1981-02-13       Impact factor: 47.728

8.  Role of positive charge on the amino-terminal region of the signal peptide in protein secretion across the membrane.

Authors:  S Inouye; X Soberon; T Franceschini; K Nakamura; K Itakura; M Inouye
Journal:  Proc Natl Acad Sci U S A       Date:  1982-06       Impact factor: 11.205

9.  Oligonucleotide directed mutagenesis of the human beta-globin gene: a general method for producing specific point mutations in cloned DNA.

Authors:  R B Wallace; M Schold; M J Johnson; P Dembek; K Itakura
Journal:  Nucleic Acids Res       Date:  1981-08-11       Impact factor: 16.971

10.  Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function.

Authors:  G Dalbadie-McFarland; L W Cohen; A D Riggs; C Morin; K Itakura; J H Richards
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205
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