Sanitization of dentures by several denture hygiene methods.

Denture sanitization is an important element in the treatment of denture stomatitis and should be emphasized in instructions to patients. A two-part study was designed to compare the efficacy of eight denture-cleaning methods in removing and/or killing aerobes, anaerobes, and yeasts on dentures. Part I tested the effectiveness of the cleaners on a pure yeast culture of C. albicans. Part II tested the various denture sanitization techniques under actual clinical conditions. The following conclusions were made from the information obtained in this study: Miller's and Kleenite were the most effective sanitizing agents. Brushing the denture with soap and water and soaking the denture in the cleaner Mersene were effective to a lesser degree. Although Clorox and Calgon was effective at killing yeast under in vitro conditions, it was not effective under clinical conditions. The other denture cleaners were not found to be effective under the clinical conditions of this study for the removal and/or killing of any of the three microorganism groups cultured. In the past, the function of denture cleaners has been to remove deposits and stains from dentures. With the present knowledge of the role of microorganisms in the etiology of denture stomatitis, more emphasis should be placed on the ability of denture cleaners to sanitize dentures.