Literature DB >> 63799

Inappropriate antihypertensive therapy in the elderly.

G Jackson, T A Pierscianowski, W Mahon, J Condon.   

Abstract

Six symptomless patients aged 64-84 (mean 72) years received antihypertensive therapy from their family doctors. Pretreatment systolic pressures ranged from 160 to 220 mm Hg and disastolic pressures from 80 to 120 mm Hg. Within one week of starting therapy all six patients were admitted as emergencies with epidoses of unconsciousness. Admission systolic pressures ranged from 80 to 150 mm Hg and diastolic pressures from 50 to 90 mm Hg. Before admission each patient had experiences symptoms of postural hypotension and had become housebound. After antihypertensive therapy was stopped, one patient had a residual left homonymous hemianopia but the others recovered completely. A raised systolic and distolic pressure is common in the elderly; potent antihypertensive treatment may seriously impair the quality of life and is often unecessary.

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Year:  1976        PMID: 63799     DOI: 10.1016/s0140-6736(76)91970-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  30 in total

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5.  Contribution of inappropriate treatment for hypertension to pathogenesis of stroke in the elderly.

Authors:  P A Jansen; F W Gribnau; B P Schulte; E F Poels
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Review 6.  Physiological changes due to age. Pharmacodynamic changes of drug action and implications for therapy.

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7.  Absence of central functional cholinergic deficits in myasthenia gravis.

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8.  Drug prescribing for the elderly in Saskatchewan during 1976.

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9.  Impact of demographic trends on cardiovascular therapy during the next decade.

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Review 10.  Drug treatment as a cause of falls in old age. A review of the offending agents.

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