Literature DB >> 6375564

In vitro antibacterial activity of the combination of clindamycin and ceftazidime.

W L George.   

Abstract

A total of 49 anaerobic and 52 aerobic or facultative bacteria were tested for their susceptibilities to clindamycin and ceftazidime alone and in combination. Synergy was noted for 11 strains, whereas antagonism was not detected. The combination of clindamycin and ceftazidime may prove to be useful for the treatment of severe mixed infections caused by anaerobes and aerobes or facultative bacteria.

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Year:  1984        PMID： 6375564      PMCID： PMC185610          DOI： 10.1128/AAC.25.5.657

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Ceftazidime--a new extended-spectrum cephalosporin.

Authors:  D I Gozzard; A M Geddes; I D Farrell; S J Eykyn; I Phillips; R Wise; R M Brown
Journal:  Lancet       Date:  1982-05-22       Impact factor: 79.321

2.  Prospective, randomized comparative study of clindamycin, chloramphenicol, and ticarcillin, each in combination with gentamicin, in therapy for intraabdominal and female genital tract sepsis.

Authors:  G K Harding; F J Buckwold; A R Ronald; T J Marrie; S Brunton; J C Koss; M J Gurwith; W L Albritton
Journal:  J Infect Dis       Date:  1980-09       Impact factor: 5.226

3.  Susceptibility of anaerobic bacteria to 23 antimicrobial agents.

Authors:  V L Sutter; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1976-10       Impact factor: 5.191

4.  Impact of cefoperazone therapy on fecal flora.

Authors:  M E Mulligan; D M Citron; B T McNamara; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1982-08       Impact factor: 5.191

5.  Intravenous metronidazole for treatment of infections involving anaerobic bacteria.

Authors:  W L George; B D Kirby; V L Sutter; L A Wheeler; M E Mulligan; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1982-03       Impact factor: 5.191

6.  A randomized comparison of cefoxitin with or without amikacin and clindamycin plus amikacin in surgical sepsis.

Authors:  F P Tally; K McGowan; J M Kellum; S L Gorbach; T F O'Donnell
Journal:  Ann Surg       Date:  1981-03       Impact factor: 12.969

7.  Antibacterial activity and beta-lactamase stability of ceftazidime, an aminothiazolyl cephalosporin potentially active against Pseudomonas aeruginosa.

Authors:  H C Neu; P Labthavikul
Journal:  Antimicrob Agents Chemother       Date:  1982-01       Impact factor: 5.191
  7 in total
  1 in total

Review 1.  Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  D M Richards; R N Brogden
Journal:  Drugs       Date:  1985-02       Impact factor: 9.546
  1 in total

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