Literature DB >> 6375492

ELISA for quantitative measurement of low-molecular-weight bronchial protease inhibitor in human sputum.

J A Kramps, C Franken, J H Dijkman.   

Abstract

A double-antibody sandwich enzyme-linked immunosorbent assay is described to quantify the low-molecular-weight bronchial protease inhibitor in sputum and other body fluids. Relatively large amounts of this inhibitor were found in sputum, saliva, nasal secretions, seminal plasma, cervical mucus, and tear fluid. The inhibitor concentration in sputum varied from 4 to 405 micrograms/ml (mean, 66 micrograms/ml). With this assay, it was shown that in sputum the inhibitor is concentrated in the mucin-containing gel phase.

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Year:  1984        PMID： 6375492     DOI： 10.1164/arrd.1984.129.6.959

Source DB:  PubMed          Journal:  Am Rev Respir Dis        ISSN： 0003-0805


  22 in total

1.  Expression of the secretory leukoprotease inhibitor gene in epithelial cells.

Authors:  T Abe; N Kobayashi; K Yoshimura; B C Trapnell; H Kim; R C Hubbard; M T Brewer; R C Thompson; R G Crystal
Journal:  J Clin Invest       Date:  1991-06       Impact factor: 14.808

2.  Detection of antileukoprotease in connective tissue of the lung.

Authors:  L N Willems; C J Otto-Verberne; J A Kramps; A A ten Have-Opbroek; J H Dijkman
Journal:  Histochemistry       Date:  1986

Review 3.  alpha-1-Antitrypsin and the pathogenesis of emphysema.

Authors:  R A Stockley
Journal:  Lung       Date:  1987       Impact factor: 2.584

Review 4.  Positive and negative aspects of the human immunodeficiency virus protease: development of inhibitors versus its role in AIDS pathogenesis.

Authors:  K Ikuta; S Suzuki; H Horikoshi; T Mukai; R B Luftig
Journal:  Microbiol Mol Biol Rev       Date:  2000-12       Impact factor: 11.056

5.  Comparison of concentrations of two proteinase inhibitors, porcine pancreatic elastase inhibitory capacity, and cell profiles in sequential bronchoalveolar lavage samples.

Authors:  H M Morrison; J A Kramps; J H Dijkman; R A Stockley
Journal:  Thorax       Date:  1986-06       Impact factor: 9.139

6.  Antibacterial activity of antileukoprotease.

Authors:  P S Hiemstra; R J Maassen; J Stolk; R Heinzel-Wieland; G J Steffens; J H Dijkman
Journal:  Infect Immun       Date:  1996-11       Impact factor: 3.441

7.  Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor.

Authors:  C Vogelmeier; R C Hubbard; G A Fells; H P Schnebli; R C Thompson; H Fritz; R G Crystal
Journal:  J Clin Invest       Date:  1991-02       Impact factor: 14.808

8.  Regulation and activity of secretory leukoprotease inhibitor (SLPI) is altered in smokers.

Authors:  Megan Meyer; Rebecca N Bauer; Blanche D Letang; Luisa Brighton; Elizabeth Thompson; Rosalia C M Simmen; James Bonner; Ilona Jaspers
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2013-11-27       Impact factor: 5.464

9.  Human bronchial leucocyte proteinase inhibitor. Rapid isolation and kinetic analysis with human leucocyte proteinases.

Authors:  C E Smith; D A Johnson
Journal:  Biochem J       Date:  1985-01-15       Impact factor: 3.857

10.  Tissue inhibitor of metalloproteinases and collagenase inhibitory activity in lung secretions from patients with chronic obstructive bronchitis: effect of corticosteroid treatment.

Authors:  D Burnett; J J Reynolds; R V Ward; S C Afford; R A Stockley
Journal:  Thorax       Date:  1986-10       Impact factor: 9.139
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