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Literature DB >> 636960

Inflammatory models in rats depleted of endogenous precursors of prostaglandins.

I L Bonta, H Bult, M J Parnham, J E Vincent.

Abstract

Inflammatory models in rats, depleted of prostaglandin precursors, are discussed as a novel approach to investigate anti-inflammatory drug mechanisms independent of interaction with the production of prostaglandins and to study the ambivalent (pro- or anti-inflammatory) role of endogenous prostaglandins.

Entities: Chemical Species

Mesh：

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Year: 1978 PMID： 636960 DOI： 10.1007/BF01972409

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

17 in total

1. Inhibition of release of prostaglandins as an explanation of some of the actions of anti-inflammatory corticosteroids.

Authors: G P Lewis; P J Piper
Journal: Nature Date: 1975-03-27 Impact factor: 49.962

2. Reduced exudation and increased tissue proliferation during chronic inflammation in rats deprived of endogenous prostaglandin precursors.

Authors: I L Bonta; M J Parnham; M J Adolfs
Journal: Prostaglandins Date: 1977-08

3. Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine.

Authors: M Di Rosa; J P Giroud; D A Willoughby
Journal: J Pathol Date: 1971-05 Impact factor: 7.996

4. Reduction of prostaglandin-phase in hind-paw inflammation and partial failure of indomethacin to exert anti-inflammatory effect in rats on essential fatty acid deficient diet.

Authors: I L Bonta; H Chrispijn; J Noordhoek; J E Vincent
Journal: Prostaglandins Date: 1974-03-10

5. Inhibition of sheep vesicular gland oxygenase by unsaturated fatty acids from skin of essential fatty acid deficient rats.

Authors: V A Ziboh; J Y Vanderhoek; W E Lands
Journal: Prostaglandins Date: 1974-02-10

6. Prostaglandins and aspirin: an alternative view.

Authors: M J Smith
Journal: Agents Actions Date: 1975-10

7. A brief survey of the history of inflammation.

Authors: M Rocha e Silva
Journal: Agents Actions Date: 1978-01

8. Acute anti-inflammatory effects of aspirin and dexamethasone in rats deprived of endogenous prostaglandin precursors.

Authors: I L Bonta; H Bult; J E Vincent; F J Zijlstra
Journal: J Pharm Pharmacol Date: 1977-01 Impact factor: 3.765

9. Corticosteroids inhibit prostaglandin release from perfused mesenteric blood vessels of rabbit and from perfused lungs of sensitized guinea pig.

Authors: R J Gryglewski; B Panczenko; R Korbut; L Grodzinska; A Ocetkiewicz
Journal: Prostaglandins Date: 1975-08