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Literature DB >> 6369322

Enhancement of spontaneous mitotic recombination by the meiotic mutant spo11-1 in Saccharomyces cerevisiae.

Abstract

Both nonreciprocal and reciprocal mitotic recombination are enhanced by the recessive mutant spo11-1, which was previously shown to affect meiosis by decreasing recombination and increasing nondisjunction. The mitotic effects are not distributed equally in all chromosomal regions. The genotypes of mitotic recombinants in spo11-1/spo11-1 diploid cells provide further evidence that widely spaced chromosomal markers undergo coincident conversion in mitosis.

Entities: Species

Mesh：

Year: 1983 PMID： 6369322 PMCID： PMC534381 DOI： 10.1073/pnas.80.24.7566

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

11 in total

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13 in total

1. Targeted DNA integration within different functional gene domains in yeast reveals ORF sequences as recombinational cold-spots.

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