| Literature DB >> 320451 |
Abstract
A procedure for detection of mutants exhibiting either enhanced or reduced spontaneous mutation during mitosis and/or meiosis has been developed to probe the joint genic control of spontaneous mutation and recombination in yeast. A semidominant mutator, rem1-1, recovered by this technique, exhibits enhanced spontaneous mutation,intragenic recombination, and intergenic recombination during mitosis. Diploids homozygous for rem1-1 exhibit normal levels of meiotic intragenic and intergenic recombination and diminished ascospore viability.Entities:
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Year: 1977 PMID: 320451 DOI: 10.1007/bf00695392
Source DB: PubMed Journal: Mol Gen Genet ISSN: 0026-8925