Literature DB >> 6361214

The genetic location of three mutations impairing penicillin production in Aspergillus nidulans.

J F Makins, G Holt, K D Macdonald.   

Abstract

Three mutations impairing penicillin production in Aspergillus nidulans, npeB, npeC and npeD, have been located on linkage groups III, IV and II, respectively, and positioned relative to other loci on these chromosomes.

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Year:  1983        PMID： 6361214     DOI： 10.1099/00221287-129-10-3027

Source DB:  PubMed          Journal:  J Gen Microbiol        ISSN： 0022-1287


  7 in total

1.  A lacZ reporter fusion method for the genetic analysis of regulatory mutations in pathways of fungal secondary metabolism and its application to the Aspergillus nidulans penicillin pathway.

Authors:  B Pérez-Esteban; E Gómez-Pardo; M A Peñalva
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

2.  A large cluster of highly expressed genes is dispensable for growth and development in Aspergillus nidulans.

Authors:  R Aramayo; T H Adams; W E Timberlake
Journal:  Genetics       Date:  1989-05       Impact factor: 4.562

3.  Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans.

Authors:  B J Weigel; S G Burgett; V J Chen; P L Skatrud; C A Frolik; S W Queener; T D Ingolia
Journal:  J Bacteriol       Date:  1988-09       Impact factor: 3.490

4.  Cloning, characterization of the acyl-CoA:6-amino penicillanic acid acyltransferase gene of Aspergillus nidulans and linkage to the isopenicillin N synthase gene.

Authors:  E Montenegro; J L Barredo; S Gutiérrez; B Díez; E Alvarez; J F Martín
Journal:  Mol Gen Genet       Date:  1990-05

5.  Resolution of chromosomes III and VI of Aspergillus nidulans by pulsed-field gel electrophoresis shows that the penicillin biosynthetic pathway genes pcbAB, pcbC, and penDE are clustered on chromosome VI (3.0 megabases).

Authors:  E Montenegro; F Fierro; F J Fernandez; S Gutiérrez; J F Martín
Journal:  J Bacteriol       Date:  1992-11       Impact factor: 3.490

6.  Beta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.

Authors:  D J Smith; M K Burnham; J H Bull; J E Hodgson; J M Ward; P Browne; J Brown; B Barton; A J Earl; G Turner
Journal:  EMBO J       Date:  1990-03       Impact factor: 11.598

7.  The Aspergillus nidulans npeA locus consists of three contiguous genes required for penicillin biosynthesis.

Authors:  A P MacCabe; M B Riach; S E Unkles; J R Kinghorn
Journal:  EMBO J       Date:  1990-01       Impact factor: 11.598
  7 in total

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