Literature DB >> 6342606

Certain mouse strains are deficient in a kidney brush-border metallo-endopeptidase activity.

J S Bond, J D Shannon, R J Beynon.   

Abstract

Preparations of microvilli from kidneys of BALB/c mice contain an alkaline metallo-endopeptidase, meprin (metallo-endopeptidase from renal tissue). Certain genealogically related inbred mice are markedly deficient in meprin activity. The meprin-deficient strains (CBA/J and C3H/HeJ) exhibit normal levels of other brush-border enzymes: alkaline phosphatase, aminopeptidase M and another proteinase, a phosphoramidon-sensitive neutral endopeptidase. Meprin deficiency cannot be attributed to a shift in pH optimum and is unlikely to be due to the presence of endogenous inhibitors.

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Year:  1983        PMID： 6342606      PMCID： PMC1154079          DOI： 10.1042/bj2090251

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

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Authors:  P T Varandani; L A Shroyer
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2.  Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.

Authors:  C DE DUVE; B C PRESSMAN; R GIANETTO; R WATTIAUX; F APPELMANS
Journal:  Biochem J       Date:  1955-08       Impact factor: 3.857

3.  Purification and properties of a peptidase acting on a synthetic substrate for collagenase from monkey kidney.

Authors:  S Aswanikumar; A N Radhakrishnan
Journal:  Biochim Biophys Acta       Date:  1975-03-28

4.  The synthesis and degradation of fructose diphosphate-aldolase and glyceraldehyde 3-phosphate dehydrogenase in rabbit liver.

Authors:  L W Johnson; S F Velick
Journal:  J Biol Chem       Date:  1972-07-10       Impact factor: 5.157

5.  An enzyme in microsomal fraction of kidney that inactivates bradykinin.

Authors:  E G Erdos; H Y Yang
Journal:  Life Sci       Date:  1967-03-15       Impact factor: 5.037

6.  Comparison of some characteristics of membrane-bound neutral proteinase activity in the microsomal fractions of rat kidney and small intestine.

Authors:  K Sogawa; Y Ichihara; K Takahashi
Journal:  J Biochem       Date:  1981-11       Impact factor: 3.387

7.  The effect of ionic environment on pig heart mitochondrial malate dehydrogenase.

Authors:  G A Place; R J Beynon
Journal:  Int J Biochem       Date:  1982

8.  Purification and characterization of a metallo-endoproteinase from mouse kidney.

Authors:  R J Beynon; J D Shannon; J S Bond
Journal:  Biochem J       Date:  1981-12-01       Impact factor: 3.857

9.  The purification and specificity of a neutral endopeptidase from rabbit kidney brush border.

Authors:  M A Kerr; A J Kenny
Journal:  Biochem J       Date:  1974-03       Impact factor: 3.857

10.  The molecular weight and properties of a neutral metallo-endopeptidase from rabbit kidney brush border.

Authors:  M A Kerr; A J Kenny
Journal:  Biochem J       Date:  1974-03       Impact factor: 3.857
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  11 in total

1.  Proteins of the kidney microvillar membrane. Purification and properties of the phosphoramidon-insensitive endopeptidase ('endopeptidase-2') from rat kidney.

Authors:  A J Kenny; J Ingram
Journal:  Biochem J       Date:  1987-07-15       Impact factor: 3.857

2.  Brush border enzyme-cleavable linkers: Evaluation for reducing renal uptake of radiolabeled prostate-specific membrane antigen inhibitors.

Authors:  Ganesan Vaidyanathan; Choong Mo Kang; Darryl McDougald; Il Minn; Mary Brummet; Martin G Pomper; Michael R Zalutsky
Journal:  Nucl Med Biol       Date:  2018-05-05       Impact factor: 2.408

3.  The metabolism of neuropeptides. Hydrolysis of peptides by the phosphoramidon-insensitive rat kidney enzyme 'endopeptidase-2' and by rat microvillar membranes.

Authors:  S L Stephenson; A J Kenny
Journal:  Biochem J       Date:  1988-10-01       Impact factor: 3.857

4.  Deficiency of membrane-bound dipeptidyl aminopeptidase IV in a certain rat strain.

Authors:  Y Watanabe; T Kojima; Y Fujimoto
Journal:  Experientia       Date:  1987-04-15

5.  The effect of synthetic analogues of chymostatin upon protein degradation in isolated skeletal muscle.

Authors:  M T Mulligan; I J Galpin; A H Wilby; R J Beynon
Journal:  Biochem J       Date:  1985-07-15       Impact factor: 3.857

6.  Mep-1 gene controlling a kidney metalloendopeptidase is linked to the major histocompatibility complex in mice.

Authors:  J S Bond; R J Beynon; J F Reckelhoff; C S David
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

7.  Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors.

Authors:  Markus-N Kruse; Christoph Becker; Daniel Lottaz; Danny Köhler; Irene Yiallouros; Hans-Willi Krell; Erwin E Sterchi; Walter Stöcker
Journal:  Biochem J       Date:  2004-03-01       Impact factor: 3.857

8.  Inherited differences in mouse kidney carnosinase activity.

Authors:  F L Margolis; M Grillo
Journal:  Biochem Genet       Date:  1984-06       Impact factor: 1.890

9.  Proteins of the kidney microvillar membrane. Structural and immunochemical properties of rat endopeptidase-2 and its immunohistochemical localization in tissues of rat and mouse.

Authors:  K Barnes; J Ingram; A J Kenny
Journal:  Biochem J       Date:  1989-12-01       Impact factor: 3.857

10.  Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge.

Authors:  Renee E Yura; S Gaylen Bradley; Ganesan Ramesh; W Brian Reeves; Judith S Bond
Journal:  Am J Physiol Renal Physiol       Date:  2008-10-29
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