Literature DB >> 6341994

Primary structure of the Saccharomyces cerevisiae gene for methionyl-tRNA synthetase.

P Walter, J Gangloff, J Bonnet, Y Boulanger, J P Ebel, F Fasiolo.   

Abstract

The sequence of a 5-kilobase DNA insert containing the structural gene for yeast cytoplasmic methionyl-tRNA synthetase has been determined and a unique open reading frame of 2,253 nucleotides encoding a polypeptide chain of 751 amino acids (Mr, 85,500) has been characterized. The data obtained on the purified enzyme (subunit size, amino acid composition, and COOH-terminal sequence) are consistent with the gene structure. The protein sequence deduced from the nucleotide sequence reveals no obvious internal repeats. This protein sequence shows a high degree of homology with that of Escherichia coli methionyl-tRNA synthetase within a region that forms the putative methionyl adenylate binding site. This strongly suggests that both proteins derive from a common ancestor.

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Year:  1983        PMID： 6341994      PMCID： PMC393840          DOI： 10.1073/pnas.80.9.2437

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  16 in total

Review 1.  How do eucaryotic ribosomes select initiation regions in messenger RNA?

Authors:  M Kozak
Journal:  Cell       Date:  1978-12       Impact factor: 41.582

2.  The taxonomy of protein structure.

Authors:  M G Rossmann; P Argos
Journal:  J Mol Biol       Date:  1977-01-05       Impact factor: 5.469

3.  Distinct nuclear genes for yeast mitochondrial and cytoplasmic methionyl-tRNA synthetases.

Authors:  J M Schneller; C Schneider; A J Stahl
Journal:  Biochem Biophys Res Commun       Date:  1978-12-29       Impact factor: 3.575

4.  Cloning of the yeast methionyl-tRNA synthetase gene.

Authors:  F Fasiolo; J Bonnet; F Lacroute
Journal:  J Biol Chem       Date:  1981-03-10       Impact factor: 5.157

5.  Methionyl-tRNA synthetase from Escherichia coli. Primary structure of the active crystallised tryptic fragment.

Authors:  D G Barker; J P Ebel; R Jakes; C J Bruton
Journal:  Eur J Biochem       Date:  1982-10

6.  Methionyl-tRNA synthetase shows the nucleotide binding fold observed in dehydrogenases.

Authors:  J L Risler; C Zelwer; S Brunie
Journal:  Nature       Date:  1981-07-23       Impact factor: 49.962

7.  Primary structure of a large aminoacyl-tRNA synthetase.

Authors:  S D Putney; N J Royal; H Neuman de Vegvar; W C Herlihy; K Biemann; P Schimmel
Journal:  Science       Date:  1981-09-25       Impact factor: 47.728

8.  Amino acid activation in crystalline tyrosyl-tRNA synthetase from Bacillus stearothermophilus.

Authors:  J Rubin; D M Blow
Journal:  J Mol Biol       Date:  1981-01-25       Impact factor: 5.469

9.  A system for shotgun DNA sequencing.

Authors:  J Messing; R Crea; P H Seeburg
Journal:  Nucleic Acids Res       Date:  1981-01-24       Impact factor: 16.971

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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  17 in total

1.  RNA binding determinant in some class I tRNA synthetases identified by alignment-guided mutagenesis.

Authors:  A Shepard; K Shiba; P Schimmel
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

2.  Purification of the heteromeric protein binding to the URS1 transcriptional repression site in Saccharomyces cerevisiae.

Authors:  R M Luche; W C Smart; T G Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

3.  Functional assembly of a randomly cleaved protein.

Authors:  K Shiba; P Schimmel
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-01       Impact factor: 11.205

4.  Diversified sequences of peptide epitope for same-RNA recognition.

Authors:  S Kim; L Ribas de Pouplana; P Schimmel
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-01       Impact factor: 11.205

5.  Cloning and characterization of the gene coding for cytoplasmic seryl-tRNA synthetase from Saccharomyces cerevisiae.

Authors:  I Weygand-Durasevic; D Johnson-Burke; D Söll
Journal:  Nucleic Acids Res       Date:  1987-03-11       Impact factor: 16.971

6.  Cloning and characterization of the gene for the yeast cytoplasmic threonyl-tRNA synthetase.

Authors:  L K Pape; A Tzagoloff
Journal:  Nucleic Acids Res       Date:  1985-09-11       Impact factor: 16.971

7.  Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes.

Authors:  P M Sharp; T M Tuohy; K R Mosurski
Journal:  Nucleic Acids Res       Date:  1986-07-11       Impact factor: 16.971

8.  Yeast omnipotent supressor SUP1 (SUP45): nucleotide sequence of the wildtype and a mutant gene.

Authors:  P Breining; W Piepersberg
Journal:  Nucleic Acids Res       Date:  1986-07-11       Impact factor: 16.971

9.  Mutations that inactivate a yeast transcriptional regulatory protein cluster in an evolutionarily conserved DNA binding domain.

Authors:  M Johnston; J Dover
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

10.  Isolation, structure and expression of mammalian genes for histidyl-tRNA synthetase.

Authors:  F W Tsui; L Siminovitch
Journal:  Nucleic Acids Res       Date:  1987-04-24       Impact factor: 16.971
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