Literature DB >> 6336967

Drug treatment of epilepsy: a review.

D Rosenbloom, A R Upton.   

Abstract

Once a decision to treat epilepsy has been made it is necessary to have a thorough knowledge of the benefits, disadvantages, toxic effects, pharmacokinetics and interactions associated with each anticonvulsant. However, by determining the serum concentration and manipulating it within the therapeutic range it should be possible to find a regimen that adequately controls seizures without introducing unnecessary toxic effects. There are special considerations in choosing anticonvulsants to treat epilepsy in pregnancy, febrile convulsions and status epilepticus.

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Year:  1983        PMID： 6336967      PMCID： PMC1874771     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN： 0008-4409            Impact factor:   8.262


  64 in total

1.  DIPHENYLHYDANTOIN METABOLISM, BLOOD LEVELS, AND TOXICITY.

Authors:  H KUTT; W WINTERS; R KOKENGE; F MCDOWELL
Journal:  Arch Neurol       Date:  1964-12

2.  Hydantoin and barbiturate blood levels observed in epileptics.

Authors:  G L PLAA; C H HINE
Journal:  Arch Int Pharmacodyn Ther       Date:  1960-11-01

3.  Chemical evidence of tolerance to phenobarbital.

Authors:  I SUNSHINE
Journal:  J Lab Clin Med       Date:  1957-07

4.  Influence of disease on binding of drugs to plasma proteins.

Authors:  M M Reidenberg; M Affrime
Journal:  Ann N Y Acad Sci       Date:  1973-11-26       Impact factor: 5.691

5.  Medical and social prognosis in epilepsy.

Authors:  E A Rodin
Journal:  Epilepsia       Date:  1972-01       Impact factor: 5.864

6.  Relation of prophylactic medication to the occurrence of early seizures following craniocerebral trauma.

Authors:  B L Rish; W F Caveness
Journal:  J Neurosurg       Date:  1973-02       Impact factor: 5.115

7.  Perceptual-motor behaviour in relation to blood phenobarbitone level: a preliminary report.

Authors:  S J Hutt; P M Jackson; A Belsham; G Higgins
Journal:  Dev Med Child Neurol       Date:  1968-10       Impact factor: 5.449

8.  Relative anticonvulsant potency of primidone; a double blind comparison.

Authors:  P T White; D Plott; J Norton
Journal:  Arch Neurol       Date:  1966-01

9.  Prognosis in childhood epilepsy. Follow-up study of 148 cases in which therapy had been suspended after prolonged anticonvulsant control.

Authors:  J Holowach; D L Thurston; J O'Leary
Journal:  N Engl J Med       Date:  1972-01-27       Impact factor: 91.245

10.  The metabolic conversion of primidone (Mysoline) to phenobarbitone in patients under long-term treatment. An attempt to estimate the independent effect of primidone.

Authors:  O V Olesen; M Dam
Journal:  Acta Neurol Scand       Date:  1967       Impact factor: 3.209
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  3 in total

Review 1.  Anticonvulsants and breast feeding: a critical review.

Authors:  B Bar-Oz; I Nulman; G Koren; S Ito
Journal:  Paediatr Drugs       Date:  2000 Mar-Apr       Impact factor: 3.022

2.  Reducing the number of anticonvulsant drugs taken by severely retarded epileptic patients.

Authors:  W J Craymer; E M Crawford; C W Gowdey
Journal:  Can Fam Physician       Date:  1984-04       Impact factor: 3.275

3.  Pharmacokinetics of phenobarbital in the cat following intravenous and oral administration.

Authors:  S M Cochrane; W D Black; J M Parent; D G Allen; J H Lumsden
Journal:  Can J Vet Res       Date:  1990-01       Impact factor: 1.310
  3 in total

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