Literature DB >> 6335711

Biological studies of a new class of technetium complexes: the hexakis(alkylisonitrile)technetium(I) cations.

A G Jones, M J Abrams, A Davison, J W Brodack, A K Toothaker, S J Adelstein, A I Kassis.   

Abstract

This study describes the preparation and synthesis of a new class of cationic technetium compounds, the hexakis(alkylisonitrile)technetium(+ 1) complexes, at both carrier added and no carrier added concentrations in aqueous media from pertechnetate. Biological distribution and imaging data in animals indicate that certain members of this class may be effective for cardiac imaging in man. The usefulness of these lipophilic water-soluble species for labeling mammalian cells is also reported.

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Year:  1984        PMID: 6335711     DOI: 10.1016/0047-0740(84)90004-4

Source DB:  PubMed          Journal:  Int J Nucl Med Biol        ISSN: 0047-0740


  35 in total

1.  A novel ternary ligand system useful for preparation of cationic (99m)Tc-diazenido complexes and (99m)Tc-labeling of small biomolecules.

Authors:  Young-Seung Kim; Zhengjie He; Wen-Yuan Hsieh; Shuang Liu
Journal:  Bioconjug Chem       Date:  2006 Mar-Apr       Impact factor: 4.774

2.  Differentiating osteoradionecrosis from nasopharyngeal carcinoma tumour recurrence using ⁹⁹Tcm-sestamibi SPECT/CT.

Authors:  A E H Tan; D C E Ng
Journal:  Br J Radiol       Date:  2011-09       Impact factor: 3.039

3.  The birth of a new radiopharmaceutical. Industrial perspective: from IND to NDA.

Authors:  L P Giering; J E Smith
Journal:  J Nucl Cardiol       Date:  1995 Jan-Feb       Impact factor: 5.952

Review 4.  Rationale for the rational development of new cardiac imaging agents.

Authors:  D D Miller
Journal:  Ann Nucl Med       Date:  1993-11       Impact factor: 2.668

5.  99mTc-MIBI (RP-30) to define the extent of myocardial ischemia and evaluate ventricular function.

Authors:  M P Larock; R Cantineau; V Legrand; H Kulbertus; P Rigo
Journal:  Eur J Nucl Med       Date:  1990

6.  Myocardial perfusion imaging with 99mTc-methoxy-isobutyl-isonitrile (MIBI): comparison of short and long time intervals between rest and stress injections. Preliminary results.

Authors:  R Taillefer; L Laflamme; G Dupras; M Picard; D C Phaneuf; J Léveillé
Journal:  Eur J Nucl Med       Date:  1988

7.  The scintigraphic evaluation of myocardial infarction and regional ventricular performance using technetium-99m hexakis (t-butylisonitrile) technetium (I) (TBI): a new myocardial imaging agent.

Authors:  S Campbell; B L Holman; J M Kirshenbaum; E M Antman; J Lister-James; A Davison; J Kozlowski; R J English; A G Jones
Journal:  Eur J Nucl Med       Date:  1986

8.  Tc-99m-N-MPO: novel cationic Tc-99m radiotracer for myocardial perfusion imaging.

Authors:  Young-Seung Kim; Jianjun Wang; Alexis Broisat; David K Glover; Shuang Liu
Journal:  J Nucl Cardiol       Date:  2008-04-21       Impact factor: 5.952

9.  Mechanism for myocardial localization and rapid liver clearance of Tc-99m-N-MPO: a new perfusion radiotracer for heart imaging.

Authors:  Young-Seung Kim; Jiyun Shi; Shizhen Zhai; Guihua Hou; Shuang Liu
Journal:  J Nucl Cardiol       Date:  2009-03-14       Impact factor: 5.952

10.  Amplitude analysis of stress technetium-99m methoxy isobutylisonitrile images in coronary artery disease.

Authors:  E E Camargo; F H Hironaka; M C Giorgi; J Soares Júnior; J C Meneguetti; R Abe; C C Robilotta; A C Munhoz; H Checchi; J A Ramirez
Journal:  Eur J Nucl Med       Date:  1992
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