Literature DB >> 6333945

Cytokines and the chronic inflammation of rheumatic disease. II. The presence of interleukin-2 in synovial fluids.

A M Nouri, G S Panayi, S M Goodman.   

Abstract

Sera and synovial fluids from patients with a variety of rheumatic diseases were assayed for interleukin-2 (IL-2) activity in a system utilizing the proliferative response of cultured human phytohaemagglutinin (PHA) T cell blasts. The synovial fluids from 14 rheumatoid arthritis, eight ankylosing spondylitis, three psoriatic arthritis and 11 osteoarthritis patients, all showed IL-2 activity. The amounts of IL-2 present in the fluids from different diseases were compared and ranged from 4.2 to 140.0 units/ml.

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Year:  1984        PMID： 6333945      PMCID： PMC1577049     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  15 in total

1.  Predominantly T-cell infiltrate in rheumatoid synovial membranes.

Authors:  J A Van Boxel; S A Paget
Journal:  N Engl J Med       Date:  1975-09-11       Impact factor: 91.245

2.  Lymphokines in the rheumatoid joint.

Authors:  P Stastny; M Rosenthal; M Andreis; M Ziff
Journal:  Arthritis Rheum       Date:  1975 May-Jun

3.  T cell growth factor: parameters of production and a quantitative microassay for activity.

Authors:  S Gillis; M M Ferm; W Ou; K A Smith
Journal:  J Immunol       Date:  1978-06       Impact factor: 5.422

4.  Continued growth of functional human T lymphocytes: production of human T-cell growth factor.

Authors:  G D Bonnard; K Yasaka; R D Maca
Journal:  Cell Immunol       Date:  1980-05       Impact factor: 4.868

5.  Ia+ T cells in synovial fluid and tissues of patients with rheumatoid arthritis.

Authors:  G R Burmester; D T Yu; A M Irani; H G Kunkel; R J Winchester
Journal:  Arthritis Rheum       Date:  1981-11

6.  Elution and characterization of lymphocytes from rheumatoid inflammatory tissue.

Authors:  T G Abrahamsen; S S Froland; J B Natvig; J Pahle
Journal:  Scand J Immunol       Date:  1975       Impact factor: 3.487

7.  Ligand-activated T cell growth factor-induced proliferation: absorption of T cell growth factor by activated T cells.

Authors:  G D Bonnard; K Yasaka; D Jacobson
Journal:  J Immunol       Date:  1979-12       Impact factor: 5.422

8.  Activated T cells in the synovial fluid of arthritic patients: characterization and comparison with in vitro activated human and murine T cells in cooperation with monocytes in cytotoxicity.

Authors:  U Galili; L Rosenthal; N Galili; E Klein
Journal:  J Immunol       Date:  1979-03       Impact factor: 5.422

9.  Biochemical characterization of lymphocyte regulatory molecules. II. Purification of a class of rat and human lymphokines.

Authors:  S Gillis; K A Smith; J Watson
Journal:  J Immunol       Date:  1980-04       Impact factor: 5.422

10.  In vitro growth of murine T cells. VI. Accelerated skin graft rejection caused by adoptively transferred cells expanded in T cell growth factor.

Authors:  M Rosenstein; T Eberlein; M M Kemeny; P H Sugarbaker; S A Rosenberg
Journal:  J Immunol       Date:  1981-08       Impact factor: 5.422
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  16 in total

1.  The effect of local anaesthetics on synoviocytes: a possible indirect mechanism of chondrolysis.

Authors:  Hillary J Braun; Benjamin T Busfield; Hyeon Joo Kim; Gaetano J Scuderi; Jason L Dragoo
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-06-21       Impact factor: 4.342

2.  Stimulation of rheumatoid synovial and blood T cells and lines by synovial fluid and interleukin-2: characterization of clones and recognition of a co-stimulatory effect.

Authors:  N Hain; S Alsalameh; W M Bertling; J R Kalden; G R Burmester
Journal:  Rheumatol Int       Date:  1990       Impact factor: 2.631

3.  Spontaneously increased B cell growth factor and B cell differentiation factor activities in the synovial fluid of patients with rheumatoid arthritis.

Authors:  J Mulero; M Alvarez-Mon; L F de Villa; M Rodríguez; E Noguera; J M Martín-Santos; C Gutiérrez
Journal:  Ann Rheum Dis       Date:  1989-05       Impact factor: 19.103

4.  Immunoregulatory lymphokines in rheumatoid joints. II. Production by and responsiveness to interleukin-2 of eluted synovial tissue cells.

Authors:  J Hovdenes; T Egeland
Journal:  Rheumatol Int       Date:  1987       Impact factor: 2.631

5.  Evidence for enhanced interleukin 2 (IL-2) secretion and IL-2 receptor presentation by synovial fluid lymphocytes in rheumatoid arthritis.

Authors:  G Lemm; H Warnatz
Journal:  Clin Exp Immunol       Date:  1986-04       Impact factor: 4.330

6.  Modulation of intestinal immune reactivity by interleukin 2. Phenotypic and functional analysis of lymphokine-activated killer cells from human intestinal mucosa.

Authors:  C Fiocchi; K R Youngman; B Yen-Lieberman; R R Tubbs
Journal:  Dig Dis Sci       Date:  1988-10       Impact factor: 3.199

Review 7.  Dendritic cells in the pathogenesis of rheumatoid arthritis.

Authors:  L M March
Journal:  Rheumatol Int       Date:  1987       Impact factor: 2.631

8.  Interleukin 2 inhibitor in synovial fluid.

Authors:  P Emery; K C Gentry; A Kelso; I R Mackay
Journal:  Clin Exp Immunol       Date:  1988-04       Impact factor: 4.330

9.  Early lymphocyte activation in the synovial microenvironment in patients with osteoarthritis: comparison with rheumatoid arthritis patients and healthy controls.

Authors:  R Rollín; F Marco; J A Jover; J A García-Asenjo; L Rodríguez; L López-Durán; B Fernández-Gutiérrez
Journal:  Rheumatol Int       Date:  2008-01-18       Impact factor: 2.631

10.  Kinetics of cytokine secretion by mononuclear cells of the blood from rheumatoid arthritis patients are different from those of healthy controls.

Authors:  S Ruschen; W Stellberg; H Warnatz
Journal:  Clin Exp Immunol       Date:  1992-07       Impact factor: 4.330
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