Literature DB >> 3313661

Dendritic cells in the pathogenesis of rheumatoid arthritis.

L M March1.   

Abstract

The cause of rheumatoid arthritis is unknown. It appears that abnormal or overstimulated cell-mediated immune mechanisms are operating. Dendritic cells, with their potent antigen presenting and immunostimulatory properties, have been found in increased numbers of rheumatoid synovial fluids and membranes. It is postulated that these cells play a key role in inducing and perpetuating the immune response with subsequent synovial proliferation and joint destruction.

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Mesh:

Year:  1987        PMID: 3313661     DOI: 10.1007/BF00270460

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN: 0172-8172            Impact factor:   2.631


  84 in total

1.  Non-adherent, low-density cells from human peripheral blood contain dendritic cells and monocytes, both with veiled morphology.

Authors:  S C Knight; J Farrant; A Bryant; A J Edwards; S Burman; A Lever; J Clarke; A D Webster
Journal:  Immunology       Date:  1986-04       Impact factor: 7.397

2.  Antigen presentation: comments on its regulation and mechanism.

Authors:  E R Unanue; D I Beller; C Y Lu; P M Allen
Journal:  J Immunol       Date:  1984-01       Impact factor: 5.422

3.  Role of prostaglandin in the depressed cell-mediated immune response in rheumatoid arthritis.

Authors:  S I Wolinsky; J S Goodwin; R P Messner; R C Williams
Journal:  Clin Immunol Immunopathol       Date:  1980-09

4.  Functional anatomy of lymph nodes. II. Peripheral lymph-borne mononuclear cells.

Authors:  R H Kelly; B M Balfour; J A Armstrong; S Griffiths
Journal:  Anat Rec       Date:  1978-01

Review 5.  Antigen-presenting cells, including Langerhans cells, veiled cells and interdigitating cells.

Authors:  B M Balfour; H A Drexhage; E W Kamperdijk; E C Hoefsmit
Journal:  Ciba Found Symp       Date:  1981

6.  Rheumatoid non-lymphoid synovial cells and the induction of mixed leukocyte reactions. Low-density preparations containing Ia+ macrophages and dendritic cells are less stimulatory than peripheral blood non-T cells.

Authors:  G R Burmester; J Schneeberger; B Jahn; M Gramatzki; J Zacher; J R Kalden
Journal:  Rheumatol Int       Date:  1984       Impact factor: 2.631

7.  Predominance of T cells in the lymphocytic infiltrates of synovial tissues in rheumatoid arthritis.

Authors:  A D Bankhurst; G Husby; R C Williams
Journal:  Arthritis Rheum       Date:  1976 May-Jun

8.  Immunogenetics of rheumatoid arthritis.

Authors:  R L Dawkins; P H Kay; F T Christiansen
Journal:  Ann Acad Med Singap       Date:  1983-04       Impact factor: 2.473

9.  Rheumatoid synovial dendritic cells as stimulators in allogeneic and autologous mixed leukocyte reactions--comparison with autologous monocytes as stimulator cells.

Authors:  K Waalen; J Thoen; O Førre; T Hovig; J Teigland; J B Natvig
Journal:  Scand J Immunol       Date:  1986-02       Impact factor: 3.487

10.  Augmented numbers of HLA-DR-positive T lymphocytes in the synovial fluid and synovial tissue of patients with rheumatoid arthritis and juvenile rheumatoid arthritis: in vivo-activated T lymphocytes are potent stimulators in the mixed lymphocyte reaction.

Authors:  O Førre; J H Dobloug; J B Natvig
Journal:  Scand J Immunol       Date:  1982-02       Impact factor: 3.487

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