| Literature DB >> 3313661 |
Abstract
The cause of rheumatoid arthritis is unknown. It appears that abnormal or overstimulated cell-mediated immune mechanisms are operating. Dendritic cells, with their potent antigen presenting and immunostimulatory properties, have been found in increased numbers of rheumatoid synovial fluids and membranes. It is postulated that these cells play a key role in inducing and perpetuating the immune response with subsequent synovial proliferation and joint destruction.Entities:
Mesh:
Year: 1987 PMID: 3313661 DOI: 10.1007/BF00270460
Source DB: PubMed Journal: Rheumatol Int ISSN: 0172-8172 Impact factor: 2.631