Literature DB >> 6331772

Amish study, IV: Genetic linkage study of pedigrees of bipolar probands.

K K Kidd, J A Egeland, L Molthan, D L Pauls, S D Kruger, K H Messner.   

Abstract

Genetic linkage studies were conducted on five Old Order Amish bipolar pedigrees in 1979 and 1982, with 94 members tested for color blindness and typed for 42 red blood cell and related markers in 17 antigen systems. Also, 59 individuals in two pedigrees were typed for HLA, Bf, and GLO. Linkage analyses assuming X-linkage and autosomal inheritance of bipolar illness were done with diagnostic schemes ranging from strict bipolar to milder forms of affective disorder. Linkage to affective disorders was not strongly supported for any marker locus. Close linkage to HLA was excluded, with weaker evidence against linkage to GLO.

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Year:  1984        PMID： 6331772     DOI： 10.1176/ajp.141.9.1042

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN： 0002-953X            Impact factor:   18.112


  5 in total

1.  Status of the search for a major genetic locus for affective disorder in the Old Order Amish.

Authors:  A J Pakstis; J R Kidd; C M Castiglione; K K Kidd
Journal:  Hum Genet       Date:  1991-08       Impact factor: 4.132

2.  A follow-up report of a genome search for affective disorder predisposition loci in the Old Order Amish.

Authors:  M C LaBuda; M Maldonado; D Marshall; K Otten; D S Gerhard
Journal:  Am J Hum Genet       Date:  1996-12       Impact factor: 11.025

3.  Writing Amish culture into genes: biological reductionism in a study of manic depression.

Authors:  J Floersch; J Longhofer; K Latta
Journal:  Cult Med Psychiatry       Date:  1997-06

4.  Identification of a recent recombination event within the human beta-globin gene cluster.

Authors:  D S Gerhard; K K Kidd; J R Kidd; J A Egeland; D E Housman
Journal:  Proc Natl Acad Sci U S A       Date:  1984-12       Impact factor: 11.205

5.  Twenty-seven protein polymorphisms by two-dimensional electrophoresis of serum, erythrocytes, and fibroblasts in two pedigrees.

Authors:  D Goldman; L R Goldin; P Rathnagiri; S J O'Brien; J A Egeland; C R Merril
Journal:  Am J Hum Genet       Date:  1985-09       Impact factor: 11.025
  5 in total

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