Literature DB >> 6330697

Homology between two EBV early genes and HSV ribonucleotide reductase and 38K genes.

T Gibson, P Stockwell, M Ginsburg, B Barrell.   

Abstract

Computer-matching of amino acid sequences predicted from the complete EBV DNA sequence against the known HSV gene sequences has revealed significant homology between two EBV reading frames and the HSV1 and HSV2 140K and 38K proteins which are associated with ribonucleotide reductase activity. The two genes are arranged tandemly as in HSV though it appears that, unlike HSV, the two mRNAs are not 3' co-terminal. We have mapped two promoters predicted from the DNA sequence for these genes and shown them to be transcribed at a similar stage in the virus life cycle to that of the HSV genes.

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Year:  1984        PMID: 6330697      PMCID: PMC318902          DOI: 10.1093/nar/12.12.5087

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  35 in total

1.  Expression of altered ribonucleotide reductase activity associated with the replication of the Epstein-Barr virus.

Authors:  B E Henry; R Glaser; J Hewetson; D J O'Callaghan
Journal:  Virology       Date:  1978-08       Impact factor: 3.616

2.  Inhibition of Epstein-Barr virus DNA synthesis and late gene expression by phosphonoacetic acid.

Authors:  W C Summers; G Klein
Journal:  J Virol       Date:  1976-04       Impact factor: 5.103

3.  Persisting oncogenic herpesvirus induced by the tumour promotor TPA.

Authors:  H zur Hausen; F J O'Neill; U K Freese; E Hecker
Journal:  Nature       Date:  1978-03-23       Impact factor: 49.962

4.  Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.

Authors:  A T Jamieson; G A Gentry; J H Subak-Sharpe
Journal:  J Gen Virol       Date:  1974-09       Impact factor: 3.891

5.  Accumulation of an mRNA and protein in interferon-treated Ehrlich ascites tumour cells.

Authors:  P J Farrell; R J Broeze; P Lengyel
Journal:  Nature       Date:  1979-06-07       Impact factor: 49.962

6.  Promoter sequences of eukaryotic protein-coding genes.

Authors:  J Corden; B Wasylyk; A Buchwalder; P Sassone-Corsi; C Kedinger; P Chambon
Journal:  Science       Date:  1980-09-19       Impact factor: 47.728

7.  Morphological transformation by DNA fragments of human herpesviruses: evidence for two distinct transforming regions in herpes simplex virus types 1 and 2 and lack of correlation with biochemical transfer of the thymidine kinase gene.

Authors:  G R Reyes; R LaFemina; S D Hayward; G S Hayward
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1980

8.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

9.  Structure of the adenovirus 2 early mRNAs.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1978-07       Impact factor: 41.582

10.  Ribonucleotide reductase activity of synchronized KB cells infected with herpes simplex virus.

Authors:  G H Cohen
Journal:  J Virol       Date:  1972-03       Impact factor: 5.103

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  31 in total

1.  Vaccinia virus-encoded ribonucleotide reductase: sequence conservation of the gene for the small subunit and its amplification in hydroxyurea-resistant mutants.

Authors:  M Slabaugh; N Roseman; R Davis; C Mathews
Journal:  J Virol       Date:  1988-02       Impact factor: 5.103

2.  Conservation of gene organization in the lymphotropic herpesviruses herpesvirus Saimiri and Epstein-Barr virus.

Authors:  U A Gompels; M A Craxton; R W Honess
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

3.  Marked variation in response of consensus binding elements for the Rta protein of Epstein-Barr virus.

Authors:  Lee-Wen Chen; Pey-Jium Chang; Henri-Jacques Delecluse; George Miller
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

4.  Genomic sequences homologous to the protein kinase region of the bifunctional herpes simplex virus type 2 protein ICP10.

Authors:  C C Smith; J P Wymer; J Luo; L Aurelian
Journal:  Virus Genes       Date:  1991-07       Impact factor: 2.332

5.  Herpes simplex virus specifies two subunits of ribonucleotide reductase encoded by 3'-coterminal transcripts.

Authors:  M A Swain; D A Galloway
Journal:  J Virol       Date:  1986-03       Impact factor: 5.103

6.  The small subunit of ribonucleotide reductase is encoded by one of the most abundant translationally regulated maternal RNAs in clam and sea urchin eggs.

Authors:  N M Standart; S J Bray; E L George; T Hunt; J V Ruderman
Journal:  J Cell Biol       Date:  1985-06       Impact factor: 10.539

7.  An unusual spliced herpes simplex virus type 1 transcript with sequence homology to Epstein-Barr virus DNA.

Authors:  R H Costa; K G Draper; T J Kelly; E K Wagner
Journal:  J Virol       Date:  1985-05       Impact factor: 5.103

8.  Epstein-Barr virus genome may encode a protein showing significant amino acid and predicted secondary structure homology with glycoprotein B of herpes simplex virus 1.

Authors:  P E Pellett; M D Biggin; B Barrell; B Roizman
Journal:  J Virol       Date:  1985-12       Impact factor: 5.103

9.  Alphaherpesviruses possess a gene homologous to the protein kinase gene family of eukaryotes and retroviruses.

Authors:  D J McGeoch; A J Davison
Journal:  Nucleic Acids Res       Date:  1986-02-25       Impact factor: 16.971

10.  Mapping of genes in BamHI fragment M of Epstein-Barr virus DNA that may determine the fate of viral infection.

Authors:  J Sample; G Lancz; M Nonoyama
Journal:  J Virol       Date:  1986-01       Impact factor: 5.103

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