| Literature DB >> 6330697 |
T Gibson, P Stockwell, M Ginsburg, B Barrell.
Abstract
Computer-matching of amino acid sequences predicted from the complete EBV DNA sequence against the known HSV gene sequences has revealed significant homology between two EBV reading frames and the HSV1 and HSV2 140K and 38K proteins which are associated with ribonucleotide reductase activity. The two genes are arranged tandemly as in HSV though it appears that, unlike HSV, the two mRNAs are not 3' co-terminal. We have mapped two promoters predicted from the DNA sequence for these genes and shown them to be transcribed at a similar stage in the virus life cycle to that of the HSV genes.Entities:
Mesh:
Substances:
Year: 1984 PMID: 6330697 PMCID: PMC318902 DOI: 10.1093/nar/12.12.5087
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971