Literature DB >> 6328930

Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters.

U Kikkawa, K Kaibuchi, M Castagna, J Yamanishi, K Sano, Y Tanaka, R Miyake, Y Takai, Y Nishizuka.   

Abstract

The phorbol ester TPA may be intercalated into the membrane phospholipid bilayer and selectively binds to every molecule of C-kinase in exhibiting its full enzymatic activity. Available evidence suggests that C-kinase is the receptive protein of this tumor promoter, and the results presented seem to provide clues for clarifying the mechanism of controlling cell growth and differentiation.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6328930

Source DB:  PubMed          Journal:  Adv Cyclic Nucleotide Protein Phosphorylation Res        ISSN： 0747-7767


  9 in total

1.  Differentiation-Associated Expression of Conventional Protein Kinase C Isoforms in Primary Cultures of Bone Marrow Cells Induced by M-CSF and G-CSF.

Authors:  Xiaohua Li; Hong Meng; Ben D Chen
Journal:  Am J Biomed Sci       Date:  2009-01-01

2.  Protein kinase C δ increases Kruppel-like factor 4 protein, which drives involucrin gene transcription in differentiating keratinocytes.

Authors:  Yap Ching Chew; Gautam Adhikary; Wen Xu; Gerald M Wilson; Richard L Eckert
Journal:  J Biol Chem       Date:  2013-04-17       Impact factor: 5.157

3.  Control of glycogen phosphorylase interconversion by phorbol esters, diacylglycerols, Ca2+ and hormones in isolated rat hepatocytes.

Authors:  G van de Werve; J Proietto; B Jeanrenaud
Journal:  Biochem J       Date:  1985-11-01       Impact factor: 3.857

4.  Effect of vasopressin on the regulation of protein synthesis initiation in liver cells.

Authors:  J Menaya; R Parrilla; M S Ayuso
Journal:  Biochem J       Date:  1988-09-15       Impact factor: 3.857

5.  Tumour-promoting phorbol esters increase basal and inhibit insulin-stimulated lipogenesis in rat adipocytes without decreasing insulin binding.

Authors:  G van de Werve; J Proietto; B Jeanrenaud
Journal:  Biochem J       Date:  1985-01-15       Impact factor: 3.857

Review 6.  Embryonal central neuroepithelial tumors: current concepts and future challenges.

Authors:  S R Vandenberg; M M Herman; L J Rubinstein
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

7.  Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60.

Authors:  A S Kraft; J B Smith; R L Berkow
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

8.  Stimulation of fatty acid synthesis by 4 beta-phorbol-12-myristate-13-acetate in isolated rat hepatocytes.

Authors:  T Nomura; M Tachibana; H Nomura; Y Hagino
Journal:  Lipids       Date:  1986-05       Impact factor: 1.880

Review 9.  Benzene-mediated protein kinase C activation.

Authors:  C Da Silva; X T Fan; M Castagna
Journal:  Environ Health Perspect       Date:  1989-07       Impact factor: 9.031
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.